Document Detail

Vancomycin-resistant Enterococcus faecium endocarditis in a premature infant successfully treated with linezolid.
MedLine Citation:
PMID:  14688576     Owner:  NLM     Status:  MEDLINE    
A 4 1/2-month-old, 26-week premature infant with multiple complications of prematurity required a central venous catheter for venous access and antibiotic treatment of bacterial nosocomial infections. He developed tricuspid valve endocarditis with vegetation caused by Enterococcus faecium resistant to ampicillin, vancomycin and quinupristin-dalfopristin but susceptible to linezolid. He was successfully treated with linezolid intravenously (7 weeks) and then orally (2 weeks).
Jocelyn Y Ang; Jorge L Lua; Daniel R Turner; Basim I Asmar
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  22     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-22     Completed Date:  2004-02-02     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1101-3     Citation Subset:  IM    
Children's Hospital of Michigan, Detroit, USA.
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MeSH Terms
Acetamides / administration & dosage*
Anti-Infective Agents / administration & dosage
Dose-Response Relationship, Drug
Drug Administration Schedule
Endocarditis, Bacterial / drug therapy*,  microbiology
Enterococcus faecium / drug effects*,  isolation & purification
Follow-Up Studies
Gram-Positive Bacterial Infections / drug therapy*,  microbiology
Infant, Newborn
Infant, Premature*
Infusions, Intravenous
Microbial Sensitivity Tests
Oxazolidinones / administration & dosage*
Risk Assessment
Treatment Outcome
Vancomycin Resistance
Reg. No./Substance:
0/Acetamides; 0/Anti-Infective Agents; 0/Oxazolidinones; 165800-03-3/linezolid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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