Document Detail


Vancomycin-resistant Enterococcus faecalis endocarditis: linezolid failure and strain characterization of virulence factors.
MedLine Citation:
PMID:  17182759     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Infective endocarditis due to vancomycin-resistant (VR) Enterococcus faecalis has only rarely been reported. We report a case of VR E. faecalis endocarditis that failed to respond to linezolid therapy, outline the virulence traits of the isolate, and review previously published cases of VR E. faecalis endocarditis.
Authors:
Constantine Tsigrelis; Kavindra V Singh; Thais D Coutinho; Barbara E Murray; Larry M Baddour
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2006-12-20
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  45     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-03-29     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  631-5     Citation Subset:  IM    
Affiliation:
Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. tsigrelis.constantine@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Acetamides / therapeutic use*
Adult
Anti-Infective Agents / therapeutic use*
Bacterial Proteins / genetics,  metabolism
Endocarditis, Bacterial / drug therapy*,  microbiology
Enterococcus faecalis / classification,  drug effects*,  pathogenicity*
Female
Gram-Positive Bacterial Infections / drug therapy,  microbiology
Humans
Oxazolidinones / therapeutic use*
Treatment Failure
Vancomycin Resistance*
Virulence
Virulence Factors / genetics,  metabolism
Grant Support
ID/Acronym/Agency:
R37 AI47923/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Acetamides; 0/Anti-Infective Agents; 0/Bacterial Proteins; 0/Oxazolidinones; 0/Virulence Factors; 165800-03-3/linezolid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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