Document Detail


Vancomycin-induced linear IgA disease with autoantibodies to BP180 and LAD285.
MedLine Citation:
PMID:  11736908     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Linear IgA disease (LAD) is an acquired autoimmune subepidermal bullous disease characterized by the linear deposition of IgA at the basement membrane zone. A minority of cases are induced by drugs, of which the most frequently implicated is vancomycin. The target antigens in idiopathic LAD are heterogeneous, but have not previously been reported in vancomycin-induced LAD. We report three cases, and in two of these we investigated the target antigens. In both we identified IgA antibodies to LAD285 and IgA and IgG antibodies (dual response) to BP180.
Authors:
R A Palmer; G Ogg; J Allen; A Banerjee; K S Ryatt; R Ratnavel; F Wojnarowska
Related Documents :
313418 - Fc receptors for iga on human b, and human non-b, non-t lymphocytes.
18432728 - Animal models of iga nephropathy.
211888 - Colostral iga, igg, and igm-iga fractions as fluorescent antibody for the detection of ...
6849328 - Iga-containing circulating immune complexes in patients with iga nephropathy.
16052608 - Synthetic bacterial lipopeptide analogs facilitate naive cd4+ t cell differentiation an...
1373398 - Characterization of a neutralizing monoclonal antibody to pasteurella haemolytica leuko...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  145     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2001-12-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  816-20     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Royal South Hants Hospital, Southampton SO14 OYG, UK. roypalmer@totlise.co.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Anti-Bacterial Agents / adverse effects*
Autoantibodies / analysis*
Autoantigens / immunology
Autoimmune Diseases / chemically induced*
Carrier Proteins*
Collagen / immunology
Cytoskeletal Proteins*
Drug Eruptions / etiology*,  immunology
Female
Humans
Immunoglobulin A / analysis*
Nerve Tissue Proteins*
Non-Fibrillar Collagens*
Skin / immunology
Skin Diseases, Vesiculobullous / chemically induced*,  immunology
Vancomycin / adverse effects*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Autoantibodies; 0/Autoantigens; 0/Carrier Proteins; 0/Cytoskeletal Proteins; 0/DST protein, human; 0/Immunoglobulin A; 0/Nerve Tissue Proteins; 0/Non-Fibrillar Collagens; 0/collagen type XVII; 1404-90-6/Vancomycin; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Expression of inducible nitric oxide synthase and nitrotyrosine in borderline leprosy lesions.
Next Document:  Anaphylaxis to 5-methoxypsoralen during photochemotherapy.