| Valvular heart disease in pergolide-treated Parkinson's disease. | |
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MedLine Citation:
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PMID: 16583734 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A 61-year-old woman with Parkinson's disease, receiving pergolide 1.75 mg four times daily, was admitted with progressive dyspnea. METHODS: Investigations revealed mitral and aortic regurgitation. She underwent surgical mitral replacement and aortic repair, but had a post-operative course characterized by repeated bouts of congestive heart failure. RESULTS: Severe tricuspid valve (TV) regurgitation developed within one month after the TV was reported on echocardiography to be relatively normal. Subsequent discontinuation of pergolide was associated with symptomatic improvement. CONCLUSIONS: This case illustrates the severity and rapidity with which cardiac valvular abnormalities can develop in patients receiving pergolide. |
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Authors:
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James Scozzafava; Jennifer Takahashi; Wendy Johnston; Lakshmi Puttagunta; W R Wayne Martin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Volume: 33 ISSN: 0317-1671 ISO Abbreviation: Can J Neurol Sci Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-04-04 Completed Date: 2006-05-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0415227 Medline TA: Can J Neurol Sci Country: Canada |
Other Details:
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Languages: eng Pagination: 111-3 Citation Subset: IM |
Affiliation:
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Division of Neurology, University of Alberta, Edmonton, Alberta, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antiparkinson Agents / therapeutic use* Female Heart Valve Diseases / chemically induced*, pathology Humans Parkinson Disease / drug therapy* Pergolide / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Antiparkinson Agents; 66104-22-1/Pergolide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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