Document Detail

Valve in Valve: Another Milestone for Transcatheter Valve Therapy.
MedLine Citation:
PMID:  23052029     Owner:  NLM     Status:  Publisher    
The first mechanical heart valve prosthesis designed by Dr Charles Hufnagel was implanted to the descending aorta of a 30 year old woman with severe aortic regurgitation in 1952(1). Eight years after the initial succesful prosthetic valve implantation, Dr Harken sutured a prosthetic valve (Starr Edwards Valve) to the aortic anulus after removing the diseased native valve. During the ensuing years different types of valves made from pyrolytic carbon were tried. Though successfully remedied the aortic valve disease, mechanical prosthesis required lifelong anticoagulation resulting in high rates of bleeding and thrombosis complications.
E Murat Tuzcu; Samir R Kapadia; Lars G Svensson
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-10
Journal Detail:
Title:  Circulation     Volume:  -     ISSN:  1524-4539     ISO Abbreviation:  Circulation     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Cleveland Clinic, Cleveland, OH.
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