Document Detail

Valve-sparing operation for aortic root aneurysm in patients with Marfan syndrome.
MedLine Citation:
PMID:  20333568     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We report our experience with aortic valve-sparing procedures in patients with Marfan syndrome and aortic root aneurysm. METHODS: Between August 2003 and July 2007, we performed aortic valve-sparing procedures in 20 patients with aortic root aneurysm resulting from Marfan syndrome. Mean age was 28 +/- 10 years (range, 10 to 57 years), and there were 9 females and 11 males. A reimplantation technique was used in 9 cases, a remodeling technique in 8 and a patch technique in 3 cases. Additional procedures included total aorta replacement in 1 patient, and aortic arch replacement plus stented elephant trunk in 2 patients. The mean follow-up time was 46 +/- 16 months (range, 17 to 64 months). RESULTS: No in-hospital or late death occurred. Reexploration for bleeding was required in one case on postoperative day 1. No valve-related complications occurred during the follow-up period. At the end of follow-up, trivial or no aortic regurgitation was demonstrated in 14 patients, mild in 4 patients, moderate in 1 and severe in 1. Two patients with moderate and severe aortic regurgitation required reoperation. CONCLUSIONS: The early and mid-term results of the valve-sparing operations were favorable, and the durability of the preserved valve should encourage use of this technique in patients with Marfan syndrome.
R Wang; W G Ma; L X Tian; L Z Sun; Q Chang
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Publication Detail:
Type:  Journal Article     Date:  2010-03-23
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  58     ISSN:  1439-1902     ISO Abbreviation:  Thorac Cardiovasc Surg     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-24     Completed Date:  2010-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  76-80     Citation Subset:  IM    
Department of Cardiovascular Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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MeSH Terms
Aortic Aneurysm / diagnosis,  etiology,  surgery*
Aortic Valve / surgery*
Aortic Valve Insufficiency / diagnosis,  etiology,  surgery*
Blood Vessel Prosthesis Implantation
Marfan Syndrome / complications*
Middle Aged
Retrospective Studies
Severity of Illness Index
Time Factors
Treatment Outcome
Vascular Surgical Procedures* / adverse effects
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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