Document Detail

Values of amniotic fluid index in cases of preterm premature rupture of membranes.
MedLine Citation:
PMID:  19196215     Owner:  NLM     Status:  MEDLINE    
AIMS: To measure the amniotic fluid index (AFI) in cases of preterm premature rupture of membranes (PPROM). METHODS: A retrospective study of pregnancies complicated with PPROM was performed. Data collected included maternal age, parity, gestational age at PPROM and at birth, and AFI on admission. Gestational age matched AFIs were obtained from a low-risk control group in a 3:1 ratio. RESULTS: One hundred and two singleton pregnancies with PPROM formed the study population. The mean gestational age at PPROM was 29+/-5.3 weeks (range: 14-36.6 weeks). The mean AFI in the PPROM and the control groups was 5.8+/-3.6 cm (0-18.5 cm) and 13.7+/-3.2 cm (7.3-24.4 cm), respectively (P<0.001). The area under the ROC curve of AFI in the prediction of PPROM was 0.95 (P<0.001). An AFI of < or =10 cm had sensitivity, specificity, positive and negative predictive values of 89.2%, 88.5%, 72.2% and 96%, respectively, in supporting the diagnosis of PPROM. CONCLUSIONS: The presence of low AFI supports the diagnosis of PPROM. ROC curve analysis revealed that an AFI < or =10 cm is the optimal cut-off value in the suspicion of PPROM.
Alina Weissmann-Brenner; Christopher O'Reilly-Green; Asaf Ferber; Michael Y Divon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  37     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-23     Completed Date:  2010-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  232-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Lenox-Hill Hospital, New York, NY 10021, USA.
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MeSH Terms
Amniotic Fluid*
Fetal Membranes, Premature Rupture / diagnosis*
Gestational Age*
Predictive Value of Tests
ROC Curve
Retrospective Studies
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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