Document Detail


Value of the urinary uric acid to creatinine ratio in term infants with perinatal asphyxia.
MedLine Citation:
PMID:  9583207     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The diagnosis of perinatal asphyxia is often inexact and present techniques for assessing its severity are unsatisfactory. The purpose of this study was to describe prospectively the value of the urinary uric acid to creatinine (UA/Cr) ratio in showing increased uric acid excretion in early spot urine samples for the identification of perinatal asphyxia, and to assess the relationship between the urinary UA/Cr ratio and the severity of hypoxic-ischemic encephalopathy. Twenty-seven fullterm infants with perinatal asphyxia were compared with 40 healthy controls. The UA/Cr ratio was higher in the asphyxiated group when compared with controls (2.11 +/- 0.83 vs 0.72 +/- 0.39 P < 0.001). Furthermore, there was a correlation between the UA/Cr ratio and the severity of the encephalopathy (r = 0.84; P < 0.001). The UA/Cr ratio was found to be a good, simple screening test for the early assessment of perinatal asphyxia.
Authors:
M Akisü; N Kültürsay
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Japonica; Overseas edition     Volume:  40     ISSN:  0374-5600     ISO Abbreviation:  Acta Paediatr Jpn     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-05-28     Completed Date:  1998-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370357     Medline TA:  Acta Paediatr Jpn     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  78-81     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Ege University Medical Faculty, Izmir, Turkey. akisu@bornova.ege.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Asphyxia Neonatorum / urine*
Birth Weight
Creatinine / urine*
Female
Gestational Age
Humans
Infant, Newborn
Male
Predictive Value of Tests
Prospective Studies
Uric Acid / urine*
Chemical
Reg. No./Substance:
60-27-5/Creatinine; 69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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