| Value of positron emission tomography in staging ocular adnexal lymphomas and evaluating their response to therapy. | |
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MedLine Citation:
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PMID: 17674923 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVE: An observational case series to assess the value of positron emission tomography (PET) in staging ocular adnexal lymphomas and evaluating their response to therapy. PATIENTS AND METHODS: The clinical records of 16 consecutive patients with ocular adnexal lymphoma for whom pretreatment and posttreatment PET scans and corresponding computed tomography (CT) and magnetic resonance imaging (MRI) scans were available were compared. RESULTS: Pretreatment PET scans demonstrated fluorine 18-fluorodeoxyglucose (FDG) positive lesions in 15 orbits of 12 patients. In 1 patient with low-grade follicular lymphoma of the orbit, PET revealed an additional focus of lymphoma in the deltoid muscle that was missed on clinical examination and conventional radiography. All of the posttreatment PET scans showed complete resolution of FDG uptake, suggesting good response to therapy. However, posttreatment CT and MRI scans demonstrated residual masses in 3 patients. CONCLUSIONS: PET is valuable for initial staging of ocular adnexal lymphomas and may be a good adjunct to conventional imaging in evaluation of response to therapy. |
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Authors:
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Isis Gayed; M Farahnaz Eskandari; Peter McLaughlin; Barbara Pro; Roxana Diba; Bita Esmaeli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye Volume: 38 ISSN: 1542-8877 ISO Abbreviation: Ophthalmic Surg Lasers Imaging Publication Date: 2007 Jul-Aug |
Date Detail:
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Created Date: 2007-08-06 Completed Date: 2007-08-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101155780 Medline TA: Ophthalmic Surg Lasers Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 319-25 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Antineoplastic Agents / therapeutic use Child, Preschool Female Fluorodeoxyglucose F18 / diagnostic use* Humans Lymphoma, Non-Hodgkin / drug therapy, pathology, radionuclide imaging* Magnetic Resonance Imaging Male Middle Aged Neoplasm Staging Orbital Neoplasms / drug therapy, pathology, radionuclide imaging* Positron-Emission Tomography* Radiopharmaceuticals / diagnostic use* Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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