| Value of noncontact mapping for identifying left ventricular scar in an ovine model. | |
| | |
MedLine Citation:
|
PMID: 15520308 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: We assessed the hypothesis that "virtual electrograms" from a noncontact mapping system (EnSite 3000) could be used to localize myocardial scar. METHODS AND RESULTS: Myocardial infarctions were induced in sheep by inflating an angioplasty balloon in the left anterior descending coronary artery for 3 hours. Scar mapping was performed on 8 sheep without inducible ventricular tachycardia by use of the noncontact mapping system and a 256-channel contact mapping system. Transmural mapping needles were inserted into myocardial regions that were (1) scarred, (2) peripheral to the scar, and (3) distant from the scar. Unipolar electrograms were exported from both systems and analyzed on a personal computer workstation. The percentage of myocardial scarring at each needle site was assessed histologically. Pearson's correlation was used to assess the degree of association between various electrogram characteristics and the presence of myocardial scarring. The only noncontact electrogram characteristic that showed any association with the presence of myocardial scarring was the negative slope duration (contact, r=0.62, P<0.001; noncontact, r=0.23, P=0.004). The other electrogram characteristics studied were electrogram maximal deflection (contact, r=0.38, P<0.001; noncontact, r=0.03, P=0.75) and minimal slope (contact, r=0.42, P<0.001; noncontact, r=0.05, P=0.54). CONCLUSIONS: Noncontact electrograms do not reliably identify ventricular scar. Alternative strategies such as importing computed tomography images into the geometry should be used when scar localization is important. |
| | |
Authors:
|
Aravinda Thiagalingam; Elisabeth M Wallace; Craig R Campbell; Anita C Boyd; Vicki E Eipper; Karen Byth; David L Ross; Pramesh Kovoor |
Related Documents
:
|
17056338 - Regular supraventricular tachycardias associated with idiopathic atrial fibrillation. 22082128 - Mineralocorticoid receptor antagonists for heart failure. 10159778 - Is there space for surgery in the treatment of tachyarrhythmias? 12891618 - The vb-1 catheter: a novel catheter for peripheral arterial revascularization. 20508188 - Cost-effectiveness of outpatient cardiac monitoring to detect atrial fibrillation after... 7791688 - New aspects in electrostimulation of the heart. |
Publication Detail:
|
Type: Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2004-11-01 |
Journal Detail:
|
Title: Circulation Volume: 110 ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2004 Nov |
Date Detail:
|
Created Date: 2004-11-16 Completed Date: 2005-06-15 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0147763 Medline TA: Circulation Country: United States |
Other Details:
|
Languages: eng Pagination: 3175-80 Citation Subset: AIM; IM |
Affiliation:
|
Cardiology Department, Westmead Hospital, Westmead, Sydney, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Balloon Dilatation / adverse effects, instrumentation Cardiac Pacing, Artificial Cicatrix / etiology, pathology* Electrophysiology / instrumentation, methods* Equipment Design Heart Catheterization / instrumentation, methods* Heart Ventricles / pathology* Imaging, Three-Dimensional* Myocardial Infarction / etiology, pathology* Sheep User-Computer Interface* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide...
Next Document: Evidence for a heritable component in death resulting from aortic and mitral valve diseases.