Document Detail

Value of left ventricular regional ejection fraction determined by real-time three-dimensional echocardiography in diagnosis of aneurysm: compared with left ventriculography.
MedLine Citation:
PMID:  20137486     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Regional ejection fraction (EF(R)) measured by real-time three-dimensional echocardiography (RT-3DE) provides a novel method for quantifying left-ventricular (LV) regional systolic function. We aimed to explore the diagnostic value of regional ejection fraction (EFR) derived from RT-3DE in detecting LV aneurysms in patients with myocardial infarction. METHODS: Thirty-eight patients with myocardial infarction were prospectively enrolled and underwent electrocardiography (ECG), two-dimensional echocardiography (2-DE), RT-3DE and left ventriculography (LVG). Subjects with a negative EFR in at least one segment on RT-3DE were considered as having a ventricular aneurysm. We compared the sensitivity, specificity, Youden's index, and positive and negative predictive values of ECG, 2-DE and RT-3DE in determining LV aneurysm with detection by LVG. RESULTS: On LVG an LV aneurysm was diagnosed in 16 (42.1%) patients. The sensitivity and specificity were 62.5% and 86.4% for ECG, 81.2% and 95.4% for 2-DE, and 100.0% and 90.9% for RT-3DE in diagnosing LV aneurysm. Youden's indexes for ECG, 2-DE and RT-3DE were 0.49, 0.77 and 0.91, respectively. Positive and negative predictive values were 76.9% and 76.0% for ECG, 92.9% and 87.5% for 2-DE, and 88.9% and 100.0% for RT-3DE. CONCLUSIONS: RT-3DE-derived EFR provides a novel, reliable index in the diagnosis of LV aneurysm and has excellent sensitivity and specificity.
Xiu-Chang Li; Cheng-Jun Yan; Gui-Hua Yao; Mei Zhang; Ji-Fu Li; Yun Zhang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  122     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-02-08     Completed Date:  2010-04-30     Revised Date:  2010-09-14    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  2981-4     Citation Subset:  IM    
Department of Cardiology, Affiliated Hospital of Taishan Medical University, Tai'an, Shandong 271000, China.
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MeSH Terms
Coronary Angiography / methods
Echocardiography, Three-Dimensional / methods*
Heart Aneurysm / diagnosis*
Middle Aged
Prospective Studies
Radionuclide Ventriculography / methods*
Stroke Volume / physiology*

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