Document Detail


Value of isometric exercise testing in the optimal timing of aortic valve replacement in aortic regurgitation.
MedLine Citation:
PMID:  6641756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the possible irreversibility of isometric exercise-induced left ventricular dysfunction in aortic regurgitation, we performed handgrip exercise tests during cardiac catheterization on 17 patients with chronic aortic regurgitation (AR-group), both preoperatively and one year after successful aortic valve replacement. Nine normal subjects served as a control group. Preoperatively, the ejection fraction decreased from 59 +/- 7% to 53 +/- 8% (P less than 0.001) in the AR-group while it remained unchanged in the control group during exercise. A positive correlation existed between the changes in the ejection fraction during pre- and postoperative exercise tests (r = 0.85, P less than 0.001), which revealed that in patients with severely depressed ejection fraction during the preoperative exercise test, the ventricular response to exercise was not totally corrected after surgery. The regression of left ventricular mass was also smaller in the patients with most depressed ventricular response to exercise preoperatively. As the isometric exercise-induced left ventricular dysfunction appears to be partly irreversible, we conclude that the valve replacement should perhaps be performed before stress-induced ventricular dysfunction has occurred. Non-invasive monitoring of ventricular response to exercise might be helpful in optimizing the timing of valve replacement in aortic regurgitation.
Authors:
H V Huikuri; M J Ikäheimo; M K Linnaluoto; J T Takkunen
Related Documents :
10090226 - Left ventricular ischemia due to coronary stenosis as an unexpected treatable cause of ...
14572316 - Feeding behaviour of free-ranging walruses with notes on apparent dextrality of flipper...
2220636 - Persistence of arrhythmia exercise response in healthy young men.
6984586 - Reproducibility of exercise-induced ventricular premature beats.
14508406 - Mri determination of muscle recruitment variations in dynamic ankle plantar flexion exe...
16720936 - Improved fatigue in individuals with multiple sclerosis after participating in a short-...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European heart journal     Volume:  4     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1984-01-27     Completed Date:  1984-01-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  632-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Angiography
Aortic Valve
Aortic Valve Insufficiency / radiography,  surgery*
Exercise Test / standards*
Female
Heart Valve Prosthesis*
Hemodynamics
Humans
Isometric Contraction
Male
Middle Aged
Postoperative Period
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Bayesian analysis of stress thallium scintigraphy for the detection of multivessel coronary disease.
Next Document:  Results of surgical therapy in patients with left ventricular aneurysm.