Document Detail


Value of exercise vectorcardiography and exercise radionuclide ventriculography in identification of coronary arterial disease in patients with left bundle branch block.
MedLine Citation:
PMID:  1791085     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twelve patients (8 male and 4 female, age ranged 39-60 years) with suspected coronary arterial disease with left bundle branch block were evaluated for ischemia by simultaneous exercise vectorcardiography and radionuclide-ventriculography. Selective coronary angiography revealed normal coronary arteries in 5 and significant coronary arterial disease in 7 patients. Radionuclide ventriculography revealed no significant difference in resting left ventricular ejection fraction in patients with normal coronary arteries (44.0 +/- 13.9%) and coronary arterial disease (45.7 +/- 11.9%). Exercise radionuclide ventriculography showed positive response suggestive of ischemia in 11 patients (11/12), including all 5 with normal coronary arteries and 6/7 with coronary arterial disease. The magnitude of spatial 'R' maximum cardiac vector in both groups at rest (normal coronary arteries: 1.61 +/- 0.22 mV, coronary arterial disease: 1.63 +/- 0.35 mV) did not show any significant difference. On exercise, the magnitude of spatial 'R' maximum cardiac vector uniformly increased in patients with normal coronary arteries (1.61 +/- 0.22 to 1.75 +/- 0.25 mV, P less than 0.01) and decreased in 6 and remained unchanged in 1 patient with coronary arterial disease (1.63 +/- 0.35 to 1.34 +/- 0.46 mV, P less than 0.01). There was no change in rotational characteristics of QRS and T loops at end exercise in either group. Our preliminary observations indicate that exercise induced alteration of the magnitude of the maximal spatial 'R' cardiac vector appears to be an useful parameter to diagnose underlying coronary arterial disease in patients with left bundle branch block. Having a high false positive response, exercise radionuclide ventriculography appears to be of limited value in these patients.
Authors:
K K Talwar; K C Goswami; V Dev; A Malhotra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  32     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1992-04-02     Completed Date:  1992-04-02     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  323-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology and Nuclear Medicine, All-India Institute of Medical Sciences, New Delhi.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bundle-Branch Block / complications*
Cardiac Output / physiology
Coronary Angiography
Coronary Disease / complications,  diagnosis*,  radiography,  radionuclide imaging*
Coronary Vessels / pathology
Exercise Test*
Female
Humans
Male
Middle Aged
Radionuclide Ventriculography / methods*
Stroke Volume / physiology
Vectorcardiography / methods*
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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