| Value of echo-Doppler derived pulmonary vascular resistance, net-atrioventricular compliance and tricuspid annular velocity in determining exercise capacity in patients with mitral stenosis. | |
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MedLine Citation:
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PMID: 17965491 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The present study sought to determine if echo-Doppler-derived pulmonary vascular resistance (PVR echo), net-atrioventricular compliance (Cn) and tricuspid peak systolic annular velocity (Sa), as parameters of right ventricular function, have value in predicting exercise capacity in patients with mitral stenosis (MS). METHODS AND RESULTS: Thirty-two patients with moderate or severe MS without left ventricular systolic dysfunction were studied. After comprehensive echo-Doppler measurements, including PVR echo, tricuspid Sa and left-sided Cn, supine bicycle exercise echo and concomitant respiratory gas analysis were performed. Measurements during 5 cardiac cycles representing the mean heart rate were averaged. Increment of resting PVR(echo) (r=-0.416, p=0.018) and decrement of resting Sa (r=0.433, p=0.013) and Cn (r=0.469, p=0.007) were significantly associated with decrease in %VO(2) peak. The predictive accuracy for %VO2 peak could increase by combining these parameters as Sa/PVR echo (r=0.500, p=0.004) or Cn. (Sa/PVR echo) (r=0.572, p=0.001) independent of mitral valve area, mean diastolic pressure gradients or presence of atrial fibrillation. CONCLUSIONS: Measurement of PVR echo, Cn and Sa might provide important information about the exercise capacity of patients with MS. |
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Authors:
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Eui-Young Choi; Jaemin Shim; Sung-Ai Kim; Chi Young Shim; Se-Jung Yoon; Seok-Min Kang; Donghoon Choi; Jong-Won Ha; Se-Joong Rim; Yangsoo Jang; Namsik Chung |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 71 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2007-10-29 Completed Date: 2008-02-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 1721-7 Citation Subset: IM |
Affiliation:
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Cardiology Division, Yonsei Cardiovascular Center and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, South Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atrioventricular Node / physiology* Blood Flow Velocity / physiology Echocardiography, Doppler Exercise Test Exercise Tolerance / physiology* Female Heart Rate / physiology Humans Lung Compliance / physiology Male Middle Aged Mitral Valve Stenosis / physiopathology* Tricuspid Valve / physiology* Vascular Resistance / physiology* Ventricular Function, Right / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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