| Value of contrast-enhanced ultrasonography for detecting renal infarcts proven by contrast enhanced CT. A feasibility study. | |
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MedLine Citation:
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PMID: 17851664 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effectiveness of contrast-enhanced ultrasonography (CEUS) in the evaluation of patients with acute renal infarcts was investigated, using contrast-enhanced helical computed tomography (CT) as the reference imaging procedure. Twenty-seven consecutive patients with acute renal infarcts detected with contrast-enhanced helical CT underwent CEUS. Digital cine-clips of CEUS were evaluated by two independent readers blinded to CT findings. Image quality was rated subjectively on a four-point scale. Then, readers were asked to assign a confidence level in diagnosis of renal infarct at the upper pole, medium portion, and lower pole of each kidney according to a five-degree scale, ranging from definitely absent to definitely present. ROC curve analysis was employed to assess the overall confidence of diagnosis of infarct, and weighted kappa values were calculated to assess inter-reader agreement. The subjective image quality of CEUS was lower than the image quality of CT at the upper poles. However, the diagnostic performance of CEUS was excellent (area under receiver-operator characteristic curve 0.992 +/- 0.006 for reader 1; 0.991 +/- 0.007 for reader 2), with very good inter-reader agreement (weighted kappa value = 0.83). CEUS is a reproducible tool to detect acute renal infarcts in men, with a diagnostic performance approaching that of CT. |
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Authors:
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Michele Bertolotto; Alberto Martegani; Luca Aiani; Roberta Zappetti; Stefano Cernic; Maria Assunta Cova |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article Date: 2007-09-13 |
Journal Detail:
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Title: European radiology Volume: 18 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-04 Completed Date: 2008-06-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 376-83 Citation Subset: IM |
Affiliation:
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UCO di Radiologia, Università di Trieste, Ospedale di Cattinara, Strada di Fiume 449, 34149 Trieste, Italy. bertolot@units.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Aged, 80 and over Contrast Media / administration & dosage* Feasibility Studies Female Humans Image Enhancement / methods Infarction / diagnosis* Kidney / blood supply, radiography*, ultrasonography* Male Microbubbles Middle Aged Observer Variation Phospholipids / diagnostic use ROC Curve Reproducibility of Results Sensitivity and Specificity Sulfur Hexafluoride / diagnostic use Tomography, Spiral Computed / methods* Ultrasonography, Doppler, Color / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Phospholipids; 0/contrast agent BR1; 2551-62-4/Sulfur Hexafluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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