Document Detail


Value of T2-weighted, first-pass and delayed enhancement, and cine CMR to differentiate between acute and chronic myocardial infarction.
MedLine Citation:
PMID:  17149626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to analyze the diagnostic accuracy of edema on T2-weighted (T2w) cardiac magnetic resonance imaging (CMR), presence of microvascular obstruction (MO) on first-pass enhancement (FPE) or on delayed enhancement (DE) CMR, and wall thinning on cine CMR to differentiate between acute (AMI) and chronic myocardial infarction (CMI) in patients with infarction on DE-CMR. Fifty patients were imaged 5 +/- 3 days (baseline) and 8 +/- 3 months (follow-up) after AMI at 1.5 T. Imaging findings were graded as present or absent in a blinded consensus reading. Edema was present at baseline in 48 (96%) patients and absent at follow-up in 49 (98%) patients. At baseline, MO was present in 29 (58%) patients on FPE-CMR and in 24 (48%) patients on DE-CMR (P = ns). At follow-up, persisting hypoenhancement was observed in ten (20%) patients on FPE-CMR, whereas two (4%) patients showed persisting hypoenhancement on DE-CMR (P<0.05). Wall thinning was present in 4 (8%) patients at baseline and in 20 (40%) patients at follow-up. Edema had high sensitivity (96%), specificity (98%), and accuracy (97%) to differentiate between AMI and CMI. Accuracy of all other imaging findings was lower compared to that of edema (P<0.001). In the presence of infarction on DE-CMR, T2w-CMR reliably differentiates between AMI and CMI.
Authors:
Alexander Stork; Kai Muellerleile; Paul M Bansmann; Joachim Graessner; Michael Kaul; Joern Kemper; Gerhard Adam; Gunnar K Lund
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-12-06
Journal Detail:
Title:  European radiology     Volume:  17     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-02-13     Completed Date:  2007-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  610-7     Citation Subset:  IM    
Affiliation:
Department of Diagnostic and Interventional Radiology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. astork@uke.uni-hamburg.de
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Chronic Disease
Diagnosis, Differential
Edema / radiography*
Female
Humans
Magnetic Resonance Angiography*
Male
Middle Aged
Myocardial Infarction / radiography*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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