| The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. | |
| | |
MedLine Citation:
|
PMID: 19779945 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: High-resolution manometry (HRM) is faster and easier to perform than conventional water perfused manometry. There is general acceptance of its usefulness in evaluating upper esophageal sphincter and esophageal body. There has been less emphasis on the use of HRM to evaluate the lower esophageal sphincter (LES) resting pressure and length, both factors important in LES barrier function. The aim of this study was to compare the resting characteristics of the LES determined by HRM and conventional manometry in the same patients. METHODS: We performed both HRM and conventional manometry including a slow motorized pull-through technique in 55 patients with foregut symptoms. The characteristics of the LES analyzed were: resting pressure, total length, and abdominal length. Four available modes of HRM analysis were used to assess resting characteristics of the LES: spatiotemporal mode using both abrupt color change and isobaric contour, line tracing, and pressure profile. The values obtained from these four HRM modes were then compared to the conventional manometry measurements. RESULTS: High-resolution manometry and conventional manometry did not differ in their measurement of LES resting pressure. LES overall and abdominal length were consistently overestimated by HRM. A variability up to 4 cm in overall length was observed and was greatest in patients with hiatal hernia (1.8 vs. 0.9 cm, p = 0.027). CONCLUSION: The current construction of the catheter and software analysis used in high-resolution manometry do not allow precise measurement of LES length. Errors in the identification of the upper border of the sphincter may compromise accurate positioning of a pH probe. |
| | |
Authors:
|
Shahin Ayazi; Jeffrey A Hagen; Joerg Zehetner; Oliver Ross; Calvin Wu; Arzu Oezcelik; Emmanuele Abate; Helen J Sohn; Farzaneh Banki; John C Lipham; Steven R DeMeester; Tom R Demeester |
Related Documents
:
|
3975855 - A new method for correlating pancreatic and biliary duct pressures and sphincter of odd... 20706075 - Rectal motility in patients with idiopathic fecal incontinence: a study with impedance ... 7350055 - Intraluminal pressure recording from the human sphincter of oddi. 16826335 - Effects and mechanisms of anal electrical stimulation on anorectal compliance and tone ... 22001745 - Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidati... 6217955 - The role of clonidine in hypertensive heart disease. influence on myocardial contractil... |
Publication Detail:
|
Type: Comparative Study; Journal Article Date: 2009-09-25 |
Journal Detail:
|
Title: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Volume: 13 ISSN: 1873-4626 ISO Abbreviation: J. Gastrointest. Surg. Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2010-01-21 Completed Date: 2010-04-02 Revised Date: 2010-08-25 |
Medline Journal Info:
|
Nlm Unique ID: 9706084 Medline TA: J Gastrointest Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 2113-20 Citation Subset: IM |
Affiliation:
|
Division of Thoracic and Foregut Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, Suite 514, Los Angeles, CA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Esophageal Sphincter, Lower / physiology* Female Gastroesophageal Reflux / physiopathology* Hernia, Hiatal / physiopathology Humans Male Manometry / methods* Middle Aged |
| Comments/Corrections | |
Comment In:
|
J Gastrointest Surg. 2010 Sep;14(9):1466-7; author reply 1468-9
[PMID:
20593307
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Intestinal Surgery for Crohn's Disease: Predictors of Recovery, Quality of Life, and Costs.
Next Document: Selective Management of Patients with Acute Biliary Pancreatitis.