| Value of EUS in Determining Curative Resectability in Reference to CT and FDG-PET: The Optimal Sequence in Preoperative Staging of Esophageal Cancer? | |
| | |
MedLine Citation:
|
PMID: 21547703 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: The separate value of endoscopic ultrasonography (EUS), multidetector computed tomography (CT), and (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the optimal sequence in staging esophageal cancer has not been investigated adequately. METHODS: The staging records of 216 consecutive operable patients with esophageal cancer were reviewed blindly. Different staging strategies were analyzed, and the likelihood ratio (LR) of each module was calculated conditionally on individual patient characteristics. A logistic regression approach was used to determine the most favorable staging strategy. RESULTS: Initial EUS results were not significantly related to the LRs of initial CT and FDG-PET results. The positive LR (LR+) of EUS-fine-needle aspiration (FNA) was 4, irrespective of CT and FDG-PET outcomes. The LR+ of FDG-PET varied from 13 (negative CT) to 6 (positive CT). The LR+ of CT ranged from 3-4 (negative FDG-PET) to 2-3 (positive FDG-PET). Age, histology, and tumor length had no significant impact on the LRs of the three diagnostic tests. CONCLUSIONS: This study argues in favor of PET/CT rather than EUS as a predictor of curative resectability in esophageal cancer. EUS does not correspond with either CT or FDG-PET. LRs of FDG-PET were substantially different between subgroups of negative and positive CT results and vice versa. |
| | |
Authors:
|
L M A Schreurs; A C J W Janssens; H Groen; P Fockens; H M van Dullemen; M I van Berge Henegouwen; G W Sloof; J Pruim; J J B van Lanschot; E W Steyerberg; J Th M Plukker |
Related Documents
:
|
2326513 - Quantitative computer-aided analysis of lung texture in chest radiographs. 9040883 - Evaluation of the painful wrist. 9106293 - Heat-stroke-induced cerebellar atrophy: clinical course, ct and mri findings. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-6 |
Journal Detail:
|
Title: Annals of surgical oncology Volume: - ISSN: 1534-4681 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9420840 Medline TA: Ann Surg Oncol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Surgery/Surgical Oncology, University Medical Center Groningen, Groningen, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Elevated Preoperative Neutrophil:Lymphocyte Ratio as a Predictor of Postoperative Disease Recurrence...
Next Document: Detection and Management of Hypothyroidism Following Thyroid Lobectomy: Evaluation of a Clinical Alg...