| Value of CT and Doppler sonography in the evaluation of hepatic vein stenosis after dual-graft living donor liver transplantation. | |
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MedLine Citation:
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PMID: 17579158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to evaluate the imaging findings and role of CT and Doppler sonography in the diagnosis of hepatic vein (HV) stenosis after dual-graft living donor liver transplantation (LDLT). MATERIALS AND METHODS: Using hepatic venography as the reference standard, 73 grafts with venographic evaluation in 43 dual-graft LDLT recipients were classified into either a stenosis (n = 39) or a nonstenosis (n = 34) group. CT scans were evaluated for relative attenuation, enhancement pattern, and HV abnormality for each graft. Doppler sonography evaluation of the flow pattern of HVs for each graft was performed. CT and Doppler sonography findings were compared in the stenosis and nonstenosis groups using the independent sample Student's t test and Fisher's exact test. Multifactorial logistic regression analysis was performed to determine the best predictors of the diagnosis of HV stenosis. RESULTS: Heterogeneous enhancement (p = 0.046), abnormal HV on CT (p = 0.025), and HV wave pattern on Doppler sonography (p = 0.005) were significant findings. The accuracy for the diagnosis of HV stenosis was 60.0% for heterogeneous enhancement, 61.5% for abnormal HV, and 66.2% for a monophasic flow pattern. Heterogeneous enhancement and HV wave pattern were significant independent findings on multifactorial logistic regression analysis. The overall accuracy of the logistic model in the diagnosis of HV stenosis was 71.7%. CONCLUSION: Although CT and Doppler sonography can be helpful in diagnosing HV stenosis, given the low accuracy of individual imaging findings, the diagnosis of HV stenosis should be made cautiously, with both CT and Doppler sonography regarded as complementary examinations. |
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Authors:
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Seung Soo Lee; Kyoung Won Kim; Seong Ho Park; Yong Moon Shin; Pyo Nyun Kim; Sung Gyu Lee; Moon-Gyu Lee |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 189 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-06-20 Completed Date: 2007-07-17 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 101-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 388-1, Pungnap-2 dong, Songpa-ku, Seoul 138-736, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Hepatic Veno-Occlusive Disease / diagnosis*, etiology* Humans Liver Transplantation / adverse effects*, radiography, ultrasonography Living Donors Male Middle Aged Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / methods* Treatment Outcome Ultrasonography, Doppler / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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