| Valsartan use in pediatric hypertension. | |
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MedLine Citation:
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PMID: 21453020 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Hypertension affects up to 5% of school-aged children and is defined by an average systolic or diastolic blood pressure greater than the 95th percentile for age, sex and height. In prepubertal children a secondary cause for hypertension including renal disease, coarctation of the aorta or endocrine disease should be excluded by appropriate evaluation. The incidence and prevalence of essential hypertension in adolescents has increased together with the increase in obesity and now accounts for at least 50% of hypertension in this age group. Many children with primary hypertension and most children with secondary causes for hypertension require drug therapy. There are numerous drug classes that are presently used to treat hypertensive pediatric patients, which include β-blockers, peripheral α-blockers, direct vasodilators, ACE inhibitors, calcium channel blockers, diuretics and ARBs. This article will review the pharmacology of the ARB valsartan with respect to its efficacy, tolerability and safe use in hypertensive pediatric patients. |
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Authors:
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Kevin Ec Meyers; Brittany Behar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Future cardiology Volume: 7 ISSN: 1744-8298 ISO Abbreviation: Future Cardiol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-04-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101239345 Medline TA: Future Cardiol Country: England |
Other Details:
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Languages: eng Pagination: 151-9 Citation Subset: IM |
Affiliation:
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Division of Pediatric Nephrology, 2nd Floor Main Building, The Children's Hospital of Philadelphia, 34th Street & Civic Center Blvd, Philadelphia, PA 19104, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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