| Valsartan: new preparation. Just a second-line antihypertensive drug. | |
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MedLine Citation:
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PMID: 10915419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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(1) Valsartan is a antihypertensive drug belonging to the family of angiotensin II receptor antagonists. (2) At a dose of 40 mg/day its antihypertensive effect is inconsistent. (3) At 80 mg/day its effect on blood pressure, its adverse effects and its contraindications (mainly pregnancy and renal artery stenosis) are similar to those of angiotensin-converting-enzyme (ACE) inhibitors, except that coughing is rarer with valsartan than with ACE inhibitors. (4) Valsartan has no demonstrated advantage over losartan, another angiotensin II antagonist. (5) Valsartan has not been shown to prevent the complications of arterial hypertension, and its use is therefore less well validated than that of diuretics and betablockers. |
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Authors:
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prescrire international Volume: 7 ISSN: 1167-7422 ISO Abbreviation: Prescrire Int Publication Date: 1998 Oct |
Date Detail:
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Created Date: 2000-06-08 Completed Date: 2000-06-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9439295 Medline TA: Prescrire Int Country: FRANCE |
Other Details:
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Languages: eng Pagination: 144-5 Citation Subset: T |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin-Converting Enzyme Inhibitors
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therapeutic use* Antihypertensive Agents / administration & dosage, adverse effects, contraindications, therapeutic use Clinical Trials as Topic Diuretics Drug Therapy, Combination Humans Hypertension / drug therapy* Tetrazoles* / administration & dosage, adverse effects, contraindications, therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents; 0/Diuretics; 0/Tetrazoles |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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