Document Detail

Validity of sleep nasendoscopy in the investigation of sleep related breathing disorders.
MedLine Citation:
PMID:  15744173     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To validate the technique of sleep nasendoscopy using target controlled infusion in symptomatic patients and a control group of asymptomatic individuals. DESIGN: Prospective cohort study. SETTING: Department of otolaryngology-head and neck surgery and anesthesia in a teaching hospital. PARTICIPANTS: Two groups of patients were compared and matched for their body mass index. The first group consisted of 53 patients with a history suggestive of obstructive sleep apnea. The second group consisted of 54 patients with partner-confirmed history of no snoring. These patients were undergoing anesthesia for other reasons. Both groups of patients were free of associated otorhinolaryngologic symptoms. MAIN OUTCOME MEASURE: Assessment of production of snoring or obstruction in patients with no documented history of snoring when sedation was administered as part of general anesthesia using target controlled infusion with propofol. RESULTS AND CONCLUSIONS: None of the patients in the asymptomatic group snored or obstructed at any level of propofol, and this was clearly significant on comparison with the symptomatic group (P < .001). All of the symptomatic patients were induced to become symptomatic (snoring/obstruction).
S Berry; G Roblin; A Williams; A Watkins; H B Whittet
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Laryngoscope     Volume:  115     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-03     Completed Date:  2005-04-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  538-40     Citation Subset:  IM    
Department of Otorhinolaryngology-Head and Neck Surgery, Singleton Hospital, Swansea, UK.
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MeSH Terms
Body Mass Index
Case-Control Studies
Hypnotics and Sedatives / administration & dosage
Middle Aged
Propofol / administration & dosage
Prospective Studies
Reproducibility of Results
Sleep / physiology
Sleep Apnea Syndromes / diagnosis*,  physiopathology
Sleep Apnea, Obstructive / diagnosis,  physiopathology
Snoring / physiopathology
Reg. No./Substance:
0/Hypnotics and Sedatives; 2078-54-8/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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