| Validity of self-reported rheumatoid arthritis in a large cohort: results from the Black Women's Health Study. | |
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MedLine Citation:
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PMID: 20191523 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the positive predictive value (PPV) of 3 case definitions of rheumatoid arthritis (RA) based on self-reported data on RA diagnosis and use of arthritis medications, and to determine whether a validated screening survey would increase the PPVs in the 3 groups. METHODS: Medical records and physician checklists were reviewed for confirmation of an RA diagnosis among a sample of Black Women's Health Study participants who reported incident RA and were categorized according to reported medications: disease-modifying antirheumatic drugs (DMARDs) (n = 102), nonsteroidal antiinflammatory drugs (NSAIDs) (n = 100), and no arthritis medications (no meds) (n = 101). PPVs for confirmed RA were calculated for each of the medication groups, both overall and according to the results of the screening survey. RESULTS: The PPVs of confirmed RA were 76%, 61%, and 29% in the DMARDs, NSAIDs, and no meds groups, respectively. After exclusion of women who reported other rheumatic conditions or who reported taking only prednisone, the PPV increased in the DMARDs group to 88%, but little improvement was seen in the other groups. The PPVs increased somewhat according to results of the screening survey for the DMARDs group (92% for positive screen versus 85% for negative screen; P = 1.00), and increased substantially for the NSAIDs group (89% versus 38%, respectively; P = 0.03), but only 43% of participants completed the survey. CONCLUSION: We found that self-report of RA, along with self-reported DMARDs, is a useful case definition for identifying confirmed RA. The validated screening survey could be useful for identifying cases of confirmed RA in some, but not all, medication groups. |
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Authors:
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Margaret K Formica; Timothy E McAlindon; Timothy L Lash; Serkalem Demissie; Lynn Rosenberg |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Studies |
Journal Detail:
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Title: Arthritis care & research Volume: 62 ISSN: 2151-4658 ISO Abbreviation: Arthritis Care Res (Hoboken) Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-01 Completed Date: 2010-04-07 Revised Date: 2011-07-22 |
Medline Journal Info:
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Nlm Unique ID: 101518086 Medline TA: Arthritis Care Res (Hoboken) Country: United States |
Other Details:
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Languages: eng Pagination: 235-41 Citation Subset: IM |
Affiliation:
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Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA. formicam@upstate.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Continental Ancestry Group* Aged Anti-Inflammatory Agents, Non-Steroidal / therapeutic use Antirheumatic Agents / therapeutic use Arthritis, Rheumatoid / diagnosis*, drug therapy, ethnology* Cohort Studies Female Humans Middle Aged Predictive Value of Tests Questionnaires / standards* Women's Health* |
| Grant Support | |
ID/Acronym/Agency:
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CA58420/CA/NCI NIH HHS; R01 CA058420-15/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Antirheumatic Agents |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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