| Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trials. | |
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MedLine Citation:
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PMID: 15167305 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study is to examine the validity of, and factors associated with, the accuracy of self-report (participant-report and proxy-report) for fractures. DESIGN: Study participants were from the Women's Health Initiative Clinical Trial and Observational Study cohorts. All women were postmenopausal; populations included American Indian, Asian/Pacific Islander, black, Hispanic, and non-Hispanic white. The average length of follow-up was 4.3 years. Self-reported fractures were adjudicated by reviewing medical records. The first adjudicated self-report of fractures for each participant was included in the analysis (n = 6,652). RESULTS: We found substantial variations in validity of self-report by the fracture site. Agreements between self-reports for single-site fractures and medical records were high for hip (78%) and forearm/wrist (81%) but relatively lower for clinical spine fractures (51%). The average confirmation rate for all single-site fractures was 71%. Misidentification of fracture sites by participants or proxy-reporters seemed to be a cause of unconfirmed self-reports. Higher confirmation rates were observed in participant-reports than in proxy-reports. Results of the multivariate analysis indicated that multiple factors, such as ethnicity, a history of osteoporosis or fractures, body mass index, years since menopause, smoking status, and number of falls in the past year were significantly (P < 0.05) related to the validity of self-report. CONCLUSION: The validity of self-reports for fracture varies by fracture sites and many other factors. The assessed validity in this study is likely conservative because some of the unconfirmed self-reports may be due to poor medical record systems. The validity of self-reports for hip and forearm/wrist fractures is high in this study, supporting their use in epidemiological studies among postmenopausal women. |
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Authors:
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Zhao Chen; Charles Kooperberg; Mary B Pettinger; Tamsen Bassford; Jane A Cauley; Andrea Z LaCroix; Cora E Lewis; Simon Kipersztok; Carolyn Borne; Rebecca D Jackson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Validation Studies |
Journal Detail:
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Title: Menopause (New York, N.Y.) Volume: 11 ISSN: 1072-3714 ISO Abbreviation: Menopause Publication Date: 2004 May-Jun |
Date Detail:
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Created Date: 2004-05-28 Completed Date: 2004-08-19 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9433353 Medline TA: Menopause Country: United States |
Other Details:
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Languages: eng Pagination: 264-74 Citation Subset: IM |
Affiliation:
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University of Arizona, Tucson, AZ, USA. zchen@u.arizona.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cohort Studies Ethnic Groups* Female Fractures, Bone / epidemiology*, ethnology, etiology, radiography Humans Medical Records Middle Aged Osteoporosis, Postmenopausal / epidemiology*, ethnology, etiology, radiography Postmenopause Questionnaires / standards* Reproducibility of Results Retrospective Studies United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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1 K01 AR02060/AR/NIAMS NIH HHS; N-01-WH-3-2115/WH/WHI NIH HHS |
| Comments/Corrections | |
Comment In:
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Menopause. 2004 May-Jun;11(3):244-5
[PMID:
15167302
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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