Document Detail


Validity of predicting left ventricular end systolic pressure changes following an acute bout of exercise.
MedLine Citation:
PMID:  22721862     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Left ventricular end systolic pressure (LV ESP) is important in assessing left ventricular performance and is usually derived from prediction equations. It is unknown whether these equations are accurate at rest or following exercise in a young, healthy population.
DESIGN: Measured LV ESP vs. LV ESP values from the prediction equations were compared at rest, 15 min and 30 min following peak aerobic exercise in 60 participants.
METHODS: LV ESP was obtained by applanation tonometry at rest, 15 min post and 30 min post peak cycle exercise.
RESULTS: Measured LV ESP was significantly lower (p<0.05) at all time points in comparison to the two calculated values. Measured LV ESP decreased significantly from rest at both the post15 and post30 time points (p<0.05) and changed differently in comparison to the calculated values (significant interaction; p<0.05). The two LV ESP equations were also significantly different from each other (p<0.05) and changed differently over time (significant interaction; p<0.05).
CONCLUSIONS: The two commonly used prediction equations did not accurately predict either resting or post exercise LV ESP in a young, healthy population. Thus, LV ESP needs to be individually determined in young, healthy participants. Non-invasive measurement through applanation tonometry appears to allow for a more accurate determination of LV ESP.
Authors:
Rebecca M Kappus; Sushant M Ranadive; Huimin Yan; Abbi D Lane; Marc D Cook; Grenita Hall; I Shevon Harvey; Kenneth R Wilund; Jeffrey A Woods; Bo Fernhall
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-06-20
Journal Detail:
Title:  Journal of science and medicine in sport / Sports Medicine Australia     Volume:  16     ISSN:  1878-1861     ISO Abbreviation:  J Sci Med Sport     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-02     Completed Date:  2013-06-10     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  9812598     Medline TA:  J Sci Med Sport     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  71-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Blood Pressure Determination / methods*
Diastole
Exercise Test*
Female
Humans
Male
Manometry
Mathematical Concepts
Predictive Value of Tests
Systole*
Ventricular Function, Left / physiology*
Young Adult
Grant Support
ID/Acronym/Agency:
HL093249-01A1/HL/NHLBI NIH HHS; R01 HL093249/HL/NHLBI NIH HHS
Comments/Corrections

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