| Validity of a modified Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy. | |
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MedLine Citation:
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PMID: 18166311 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The only validated nausea and vomiting of pregnancy (NVP) severity index is the Motherisk Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) index that covers symptoms in the previous 12 hours. We sought to assess the validity of a modified-PUQE index that covers the entire first trimester of pregnancy by comparing NVP severity scores between the 12-hour PUQE index and our modified-PUQE index and by measuring the extent of the association between the modified-PUQE score and quality-of-life (QOL) score during the first trimester of pregnancy. STUDY DESIGN: A prospective study that included women who attended the Centre Hospitalier Universitaire Sainte-Justine or René-Laennec clinic for their prenatal visits was conducted from 2004-2006. Women were eligible if they were > or = 18 years old and < or = 16 weeks of gestation at the time of their first prenatal visit. Women who reported NVP were asked to fill out the 12-hour PUQE, the modified PUQE index, and the Short-Form Health Survey QOL index simultaneously. Intraclass correlation coefficients were calculated to determine concordance between the 2 scores. Linear regression models were built to measure the association between the modified-PUQE score and Short-Form Health Survey QOL scores. RESULTS: Among participants (n = 287), the mean NVP severity score was 5.7 vs 6.7 on the 12-hour PUQE and modified PUQE, respectively (P < .05). There was substantial concordance between the indices (intraclass correlation coefficient, 0.71). Severity of NVP that was measured by the new modified index was associated with QOL. CONCLUSION: We are confident that, on the basis of the modified-PUQE, the relationship between QOL and severity of NVP justify the use of this new index. |
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Authors:
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Anaïs Lacasse; Evelyne Rey; Ema Ferreira; Caroline Morin; Anick Bérard |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Studies |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 198 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-01 Completed Date: 2008-01-28 Revised Date: 2008-11-13 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 71.e1-7 Citation Subset: AIM; IM |
Affiliation:
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Faculty of Pharmacy, University of Montreal, Montreal, QC, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female France Humans Hyperemesis Gravidarum / diagnosis* Nausea / diagnosis* Pregnancy Pregnancy Trimester, First Probability Prospective Studies Quality of Life* Sensitivity and Specificity Severity of Illness Index* Sickness Impact Profile Vomiting / diagnosis* |
| Comments/Corrections | |
Comment In:
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Am J Obstet Gynecol. 2008 Oct;199(4):e10; author reply e10-1
[PMID:
18603223
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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