Document Detail

Validity of death and stillbirth certificates and hospital discharge summaries for the identification of neural tube defects in Quebec City.
MedLine Citation:
PMID:  17306063     Owner:  NLM     Status:  MEDLINE    
The objectives of this study were 1) to assess the validity of different databases which identify neural tube defect (NTD) cases in the population, and 2) to examine the temporal trends in NTD rates and the impact of prenatal diagnoses among pregnancies referred to a tertiary care hospital in Quebec City, Canada, from 1993 to 2002. Infant death and stillbirth certificates were a highly reliable source for ascertaining NTD cases, but their overall sensitivity was poor (13 percent). Med-Echo had very good sensitivity (92 percent), but there were many coding errors in the database and some diagnostic categories were not specific for NTD. The average NTD prevalence proportion was 6.5/1,000 births during the entire study period, decreasing from 12.2/1,000 in 1993 to 3.9/1,000 in 2002. Overall, 78.6 percent of NTD cases were diagnosed prenatally and the pregnancy was terminated in 52.6 percent of these. These two proportions were stable over the study years. To conclude, the combination of hospital discharge summaries and infant death and stillbirth certificates is a highly sensitive method for the ascertainment of NTD cases, including terminations of pregnancies, but medical records must be reviewed to exclude coding errors and to clarify unspecific diagnostic categories.
Fassiatou Tairou; Philippe De Wals; Adrien Bastide
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Chronic diseases in Canada     Volume:  27     ISSN:  0228-8699     ISO Abbreviation:  Chronic Dis Can     Publication Date:  2006  
Date Detail:
Created Date:  2007-02-19     Completed Date:  2007-07-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506870     Medline TA:  Chronic Dis Can     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  120-4     Citation Subset:  IM    
Department of Social and Preventive Medicine, Laval University, Quebec City, Quebec, Canada.
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MeSH Terms
Abortion, Induced / trends
Birth Certificates*
Death Certificates*
Fetal Diseases / diagnosis,  epidemiology
Forms and Records Control
International Classification of Diseases
Medical Records Systems, Computerized*
Neural Tube Defects / diagnosis*,  epidemiology,  mortality*
Patient Discharge*
Predictive Value of Tests
Prenatal Diagnosis / trends
Quebec / epidemiology
Reproducibility of Results
Stillbirth / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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