Document Detail

Validity of brief food frequency questionnaire for estimation of dietary intakes of folate, vitamins B6 and B12, and their associations with plasma homocysteine concentrations.
MedLine Citation:
PMID:  20078232     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Low nutrient intakes of folate, vitamins B(6) and B(12) have been associated with the risk of chronic diseases and neural tube defects. The aim of this study was to develop a brief food frequency questionnaire (FFQ) for the assessment of these nutrient intakes and to assess its validity. METHODS: We developed a brief FFQ designed specifically for estimating intakes of folate and vitamins B(6) and B(12) and covering 21 food items, and used it to carry out dietary surveys of 579 Japanese men and women. The associations of these vitamin intakes with their serum levels and homocysteine concentrations were examined using multiple linear regression analysis after adjusting for sex, age and cardiovascular risk factors. RESULTS: The Spearman correlation coefficients between vitamin intakes and their serum concentrations were 0.10 for folate, 0.08 for vitamin B(6) and 0.22 for B(12). Changes in plasma homocysteine concentrations associated with a one-standard-deviation increment were -0.03 for dietary folate, -0.03 for dietary vitamin B(6) and -0.03 for dietary vitamin B(12), and were -0.06 for serum folate, -0.03 for serum vitamin B(6) and -0.06 for serum vitamin B(12). CONCLUSION: Positive correlations between dietary intakes estimated from our brief FFQ and serum concentrations for folate and vitamin B(12) as well as negative correlations between dietary intakes and plasma homocysteine concentrations suggest the usefulness of this questionnaire.
Kaori Yoshino; Midori Nishide; Tomoko Sankai; Mieko Inagawa; Kimiko Yokota; Yuri Moriyama; Ai Ikeda; Hiroyuki Noda; Kazumasa Yamagishi; Takeshi Tanigawa; Hiroyasu Iso
Publication Detail:
Type:  Journal Article; Validation Studies    
Journal Detail:
Title:  International journal of food sciences and nutrition     Volume:  61     ISSN:  1465-3478     ISO Abbreviation:  Int J Food Sci Nutr     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-18     Completed Date:  2010-04-28     Revised Date:  2010-05-14    
Medline Journal Info:
Nlm Unique ID:  9432922     Medline TA:  Int J Food Sci Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  61-7     Citation Subset:  IM    
Department of Food and Nutrition, Faculty of Contemporary Human Life Science, Tezukayama University, Nara, Japan.
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MeSH Terms
Diet Surveys
Folic Acid / administration & dosage,  blood
Homocysteine / blood*
Middle Aged
Nutrition Assessment*
Reproducibility of Results
Statistics, Nonparametric
Vitamin B 12 / administration & dosage,  blood
Vitamin B 6 / administration & dosage,  blood
Vitamin B Complex / administration & dosage*,  blood*
Reg. No./Substance:
12001-76-2/Vitamin B Complex; 454-28-4/Homocysteine; 59-30-3/Folic Acid; 68-19-9/Vitamin B 12; 8059-24-3/Vitamin B 6
Erratum In:
Int J Food Sci Nutr. 2010 Jun;61(4):440
Note: Sankai, Tomoko [added]

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