Document Detail

Validity of body mass index and waist circumference to detect excess fat mass in children aged 7-14 years.
MedLine Citation:
PMID:  21048772     Owner:  NLM     Status:  In-Process    
BACKGROUND/OBJECTIVES: To evaluate the screening performance of body mass index (BMI) and waist circumference (WC) for excess adiposity. In addition, the diagnostic accuracy of cutoffs from different international and national reference systems based on BMI and WC was investigated.
SUBJECTS/METHODS: Data from 2132 Jena children aged 7-14 years conducted in 2005/2006 were analyzed. Receiver operating characteristic (ROC) curves were constructed to assess BMI and WC, as screening measures for excess adiposity (derived from skinfolds). Sensitivity, specificity and positive predictive values (PPVs) were calculated for two BMI-based classification systems (IOTF and German reference) and sample-based WC cutoffs.
RESULTS: The BMI as well as the WC performed well in detecting excess fat mass, indicated by areas under the ROC curve (AUC) close to 1.0, with slightly greater AUCs for BMI than for WC in both sexes. The specificity of all reference systems was high for both sexes (95 to 98%). However, their sensitivities were low (53-67% in boys; 51-67% in girls). PPV were higher for the German reference and the sample-based WC cutoffs than for the IOTF reference, and higher in girls than in boys.
CONCLUSIONS: The setting in which the reference system should be used is important for the selection of the reference system. The results support the use of the BMI-based references for monitoring in epidemiological studies. The sample-based cutoffs for WC should be refined for clinical use on national level.
N Glässer; K Zellner; K Kromeyer-Hauschild
Publication Detail:
Type:  Journal Article     Date:  2010-11-03
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  65     ISSN:  1476-5640     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  151-9     Citation Subset:  IM    
Institute of Human Genetics, University Hospital-Friedrich Schiller University Jena, Kollegiengasse 10, Jena, Germany.
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