| Validity of arterialized earlobe blood gases at rest and exercise in normoxia and hypoxia. | |
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MedLine Citation:
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PMID: 20493971 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to compare arterial and arterialized blood gases during normoxic and hypoxic exercise. In the same conditions, earlobe pulse oximetry O(2) saturation (Sp(O2)) was compared to arterial oxygen saturation (Sa(O2)). Ten men performed incremental cycle ergometer tests, in normoxia and hypoxia (FI(O2) = 0.127). Blood samples were drawn simultaneously from the radial artery and pre-warmed earlobe capillary blood of subjects at rest, submaximal and near maximal exercise. R(2) between the two samples were 0.99 for P(O2) and S(O2), 0.86 for P(CO2) and 0.97 between Sp(O2) and Sa(O2). Earlobe P(O2) mean was 4.4+/-3.6 mmHg lower than Pa(O2) in normoxia but in hypoxia only 1.1+/-2.2 mmHg low. The mean difference were low in normoxia between Sa(O2) and Sp(O2) and increased in hypoxia, were acceptable for P(CO2), S(O2), pH in all conditions. In conclusion, except for P(O2) in normoxia, pre-warmed earlobe capillary blood is a good substitute to arterial blood to allow measurement of blood gas values in normoxia and hypoxia at rest and exercise. |
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Authors:
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Pascal Mollard; Nicolas Bourdillon; Muriel Letournel; Harold Herman; Stéphanie Gibert; Aurélien Pichon; Xavier Woorons; Jean-Paul Richalet |
Publication Detail:
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Type: Journal Article Date: 2010-05-21 |
Journal Detail:
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Title: Respiratory physiology & neurobiology Volume: 172 ISSN: 1878-1519 ISO Abbreviation: Respir Physiol Neurobiol Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-12 Completed Date: 2010-10-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101140022 Medline TA: Respir Physiol Neurobiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 179-83 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Université Paris 13, Laboratoire Réponses cellulaires et fonctionnelles à l'hypoxie, EA2363, ARPE, Bobigny Cedex, France. pascal.mollard@laposte.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anoxia / blood* Blood Gas Analysis / methods, standards* Carbon Dioxide / blood Ear, External / blood supply* Exercise / physiology* Exercise Test Humans Hydrogen-Ion Concentration Male Oximetry Oxygen / blood Pulmonary Gas Exchange / physiology Regional Blood Flow Reproducibility of Results Rest / physiology* Young Adult |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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