Document Detail

Validation of transthoracic tissue Doppler assessment of left atrial appendage function.
MedLine Citation:
PMID:  17484993     Owner:  NLM     Status:  MEDLINE    
This study aimed to validate left atrial (LA) wall contraction velocity during atrial contraction (LAWV) in assessing LA function in 22 patients with paroxysmal atrial fibrillation. LAWV at the posterobasal LA wall was measured by transthoracic tissue Doppler echocardiography. LAWV was lower in patients with paroxysmal atrial fibrillation than in control subjects. It was more correlated with LA appendage velocity (r = 0.81) and fractional shortening (r = 0.85) than with parameters related to mitral inflow velocity or ring motion. With a LAWV cut-off value of 1.0 cm/s, receiver operator characteristic analysis curve showed a diagnostic sensitivity of 92% and a specificity of 80% in the identification of patients with spontaneous echocontrast. Among 8 patients with LAWV < or = 1.0 cm/s, cerebral embolism was evident in 3 and LA thrombus in 2, whereas the patients with LAWV greater than 1.0 cm/s had neither. LAWV may be useful to evaluate LA function and risk of embolism.
Naoyasu Yoshida; Mitsunori Okamoto; Shintaro Beppu
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Publication Detail:
Type:  Journal Article; Validation Studies    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  20     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-05-08     Completed Date:  2007-06-05     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  521-6     Citation Subset:  IM    
Echocardiography Division, Department of Laboratory Medicine, Hiroshima Prefectural Hospital, Hiroshima, Japan. <>
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MeSH Terms
Atrial Appendage / physiopathology*,  ultrasonography
Atrial Fibrillation / complications,  physiopathology*,  ultrasonography
Atrial Function, Left / physiology*
Blood Flow Velocity / physiology
Echocardiography, Doppler / methods*
Echocardiography, Transesophageal / methods
Follow-Up Studies
Intracranial Embolism / etiology
Middle Aged
Myocardial Contraction / physiology*
Observer Variation
Risk Factors
Sensitivity and Specificity
Tachycardia, Paroxysmal / complications,  physiopathology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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