Document Detail

Validation of a soy questionnaire with repeated dietary recalls and urinary isoflavone assessments over one year.
MedLine Citation:
PMID:  15087262     Owner:  NLM     Status:  MEDLINE    
This study assessed the validity and reliability of a 12-item soy questionnaire designed for use in cancer prevention research. The questionnaire measures soy intake over the past year. Subjects were 199 healthy 35- to 46-yr-old premenopausal women participating in an ongoing soy intervention study. Soy questionnaire estimates of isoflavone intake over 1 yr were compared with individual and combined estimates from two reference measures covering the same period: three or four repeated 24-h recalls and one or two repeated urine analyses. The sensitivity and specificity of the soy questionnaire in classifying high vs. low exposure (high exposure = soy intervention group membership) were comparable with 24-h recalls and were superior to urine analyses (sensitivity = 94.8%, 97.9%, and 71.1%; specificity = 95.1%, 97.1%, and 90.3% for the soy questionnaire, 24-h recalls, and urine analyses, respectively). Soy questionnaire isoflavone estimates were highly correlated with the combination of the two reference measures for the entire study population. Its brevity, ease of administration, and good measurement properties over a 1-yr period make the soy questionnaire well suited to the needs of researchers who wish to identify high and low consumers of soy foods, especially in populations who consume traditional Asian soy foods.
Andrew E Williams; Gertraud Maskarinec; Sandra Hebshi; Caryn Oshiro; Suzanne Murphy; Adrian A Franke
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Validation Studies    
Journal Detail:
Title:  Nutrition and cancer     Volume:  47     ISSN:  0163-5581     ISO Abbreviation:  Nutr Cancer     Publication Date:  2003  
Date Detail:
Created Date:  2004-04-16     Completed Date:  2004-12-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7905040     Medline TA:  Nutr Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  118-25     Citation Subset:  IM    
Cancer Research Center of Hawaii, Honolulu, HI 96813, USA.
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MeSH Terms
Biological Markers / urine
Isoflavones / administration & dosage*,  urine*
Mental Recall
Middle Aged
Questionnaires / standards*
Randomized Controlled Trials as Topic / methods
Reproducibility of Results
Sensitivity and Specificity
Soybeans* / metabolism
Grant Support
Reg. No./Substance:
0/Biological Markers; 0/Isoflavones

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