Document Detail

Validation of a semi-quantitative food frequency questionnaire measuring dietary vitamin K intake in elderly people.
MedLine Citation:
PMID:  19559145     Owner:  NLM     Status:  MEDLINE    
The study objective was to validate a semi-quantitative food frequency questionnaire (FFQ) specifically designed to measure dietary vitamin K intake. A 50-item FFQ was interviewer-administered and compared with data previously obtained from 5-day food records. Thirty-nine community-dwelling healthy men and women aged 65 to 85 years were recruited from the Montréal metropolitan area. Absolute and relative agreements between methods were assessed. Vitamin K intake measured by the vitamin K FFQ (mean+/-standard deviation; 222+/-186 microg/day) was significantly higher than that obtained by food records (135+/-153 microg/day; P<0.001). Bland-Altman analysis on log(10)-transformed data indicated that vitamin K intake from vitamin K FFQ was 2.26 times (95% confidence interval: 1.90 to 2.67) higher than food records, limits of agreement ranging from 0.80 to 6.35. However, correlation between methods was strong and highly significant (r=0.83; P<0.001). Cross-classification also showed that 72% of participants were correctly classified into thirds and only 8% were grossly miscategorized. Weighted kappa value (kappa=0.60) also indicated a good relative agreement. In light of these results, the vitamin K FFQ is a valid tool for ranking individuals according to their vitamin K intake. The poor absolute agreement likely results from the inability for food records to adequately measure the usual intake of episodically consumed foods, particularly those high in vitamin K. The vitamin K FFQ will be useful in large-scale, population-based research on vitamin K and disease as well as in clinical practice, especially that focusing on anticoagulant therapy.
Nancy Presse; Bryna Shatenstein; Marie-Jeanne Kergoat; Guylaine Ferland
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Journal of the American Dietetic Association     Volume:  109     ISSN:  1878-3570     ISO Abbreviation:  J Am Diet Assoc     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-29     Completed Date:  2009-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503061     Medline TA:  J Am Diet Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1251-5     Citation Subset:  AIM; IM    
Centre de recherche, Institut universitaire de gériatrie de Montréal and Département de nutrition, Université de Montréal, Montréal, Canada.
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MeSH Terms
Aged, 80 and over
Antifibrinolytic Agents / administration & dosage*
Diet Records
Geriatric Assessment*
Nutrition Assessment*
Nutritional Requirements
Questionnaires / standards*
Reproducibility of Results
Sensitivity and Specificity
Vitamin K / administration & dosage*
Vitamin K Deficiency / diagnosis
Reg. No./Substance:
0/Antifibrinolytic Agents; 12001-79-5/Vitamin K

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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