| Validation of the rosette inhibition test for the detection of early pregnancy in women. | |
| | |
MedLine Citation:
|
PMID: 6177559 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The authors validated use of the rosette inhibition test for the detection of early pregnancy factor (EPF) in human pregnancy, first by optimizing conditions for the assay, using known pregnant and nonpregnant sera, and second, by examining the performance of this assay in three clinical situations: a "blind" study involving coded first-trimester sera showed 80% correlation with pregnancy status; serial assay of EPF activity in sera collected from normal women attempting to conceive, correlated with human chorionic gonadotropin beta-subunit (beta-hCG) levels and pregnancy status; a longitudinal study of serial serum samples through two normal pregnancies showing the continued presence of EPF until the early third trimester in each case. It was concluded that with the rosette inhibition assay, consistent demonstration of a pregnancy-associated substance (EPF) could be obtained. |
| | |
Authors:
|
Y C Smart; T K Roberts; I S Fraser; A W Cripps; R L Clancy |
Related Documents
:
|
12095489 - Elevated serum progesterone-to-estradiol ratio during gonadotropin stimulation for intr... 2458379 - Trophoblastic and decidual response to ru486: effects on human chorionic gonadotrophin,... 14691989 - Maternal midtrimester free beta-hcg and afp serum levels in spontaneous singleton pregn... 2776959 - Serum progesterone and human chorionic gonadotropin in very early pregnancy: implicatio... 3690459 - Failure of daily measurements of hcg in urine to demonstrate a high rate of early embry... 17574609 - Fetal distribution of 5alpha-reductase 1 and 5alpha-reductase 2, and their input on hum... 6106609 - The significance of baseline tachycardia in the postterm fetus. 23132119 - Environmental risk factors and perinatal outcomes in preterm newborns, according to fam... 3974959 - Prenatal care and perinatal mortality in a black population. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Fertility and sterility Volume: 37 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1982 Jun |
Date Detail:
|
Created Date: 1982-08-14 Completed Date: 1982-08-14 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 779-85 Citation Subset: IM; J |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chaperonin 10 Chorionic Gonadotropin / blood Chorionic Gonadotropin, beta Subunit, Human Female Humans Immunosuppressive Agents / blood* Longitudinal Studies Lymphocytes / immunology Menstruation Peptide Fragments / blood Peptides* Pregnancy Pregnancy Proteins* Pregnancy Tests, Immunologic / methods* Rosette Formation* Suppressor Factors, Immunologic* |
| Chemical | |
Reg. No./Substance:
|
0/Chaperonin 10; 0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Immunosuppressive Agents; 0/Peptide Fragments; 0/Peptides; 0/Pregnancy Proteins; 0/Suppressor Factors, Immunologic; 0/early pregnancy factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adjuvant arthritis: immunopathological and hyperalgesic features.
Next Document: Transplantation antigens and keratoplasty.