Document Detail


Validation of a questionnaire and microenvironmental model for estimating past exposures to ozone.
MedLine Citation:
PMID:  12909556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epidemiology studies of the health effects associated with chronic exposure to ozone are constrained by a lack of validated exposure assessment methods that account for activity patterns and building ventilation, two potentially important predictors of ozone exposure. A pilot study was conducted to evaluate the impact of these parameters on an exposure model, to evaluate how reliably they can be reconstructed, and how this reliability affects estimates of past exposures to ozone. Fourteen subjects completed time-activity diaries and wore personal passive monitors during summer 1996 and reconstructed their activities 1 year later in a questionnaire. These data were used in a microenvironmental exposure model and the results were compared to measured personal exposure. A model using activity patterns, building ventilation, and location-specific ambient ozone data produced mean exposure estimates 18.9 +/- 1.5 ppb ozone greater than personal measurements. A simpler model that omitted variation in indoor ventilation produced exposure estimates 5.0 +/- 1.3 ppb ozone greater than mean measured exposures. The questionnaire was a reliable survey method for reconstructing past activity patterns. However, detailed histories of building ventilation may not be required to reconstruct reliably past exposures to ozone. The simple model was more precise and more practical for implementation in large epidemiological studies of health effects related to chronic exposure to ambient ozone.
Authors:
Melissa Gonzales; Long Ngo; S Katharine Hammond; Ira Tager
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  International journal of environmental health research     Volume:  13     ISSN:  0960-3123     ISO Abbreviation:  Int J Environ Health Res     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-11     Completed Date:  2004-01-29     Revised Date:  2009-08-14    
Medline Journal Info:
Nlm Unique ID:  9106628     Medline TA:  Int J Environ Health Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  249-60     Citation Subset:  IM    
Affiliation:
University of New Mexico, School of Medicine, Department of Internal Medicine, Albuquerque, NM 87131-0001, USA. mgonzales@salud.unm.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Air Pollutants / toxicity*
California / epidemiology
Environmental Exposure / statistics & numerical data*
Environmental Monitoring / standards
Female
Humans
Male
Models, Statistical
Ozone / analysis,  toxicity*
Pilot Projects
Prospective Studies
Questionnaires / standards*
Reproducibility of Results
Retrospective Studies
Chemical
Reg. No./Substance:
0/Air Pollutants; 10028-15-6/Ozone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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