Document Detail

Validation of a model predicting spontaneous pregnancy among subfertile untreated couples.
MedLine Citation:
PMID:  12215324     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To provide external validation of the Eimers model, which predicts spontaneous pregnancy among subfertile couples within the first year after the definitive establishment of the diagnostic category. DESIGN: Live birth rates predicted by an adapted version of the Eimers model were tested against observed live birth rates in a Canadian cohort study. SETTING: Fertility clinics in university medical centers. PATIENT(S): One thousand sixty-one couples consulting for subfertility due to cervical hostility, male subfertility, or unexplained subfertility. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We measured the discriminative ability and reliability of the predictions from the model. RESULT(S): The live birth rate was lower in the Canadian population than in the Eimers population. Overall, the prognostic effect of the predictors did not differ significantly in both populations. The model showed moderate predictive power in the Canadian population. With adjustment of the average live birth rate, the reliability of the model was satisfactory. CONCLUSION(S): The Eimers model gave reliable spontaneous pregnancy predictions in the Canadian validation population after adjustment of the average live birth rate.
Claudine C Hunault; Marinus J C Eijkemans; Egbert R te Velde; John A Collins; J Dik F Habbema
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  78     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-09-06     Completed Date:  2002-10-30     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  500-6     Citation Subset:  IM    
Center for Clinical Decision Sciences, Department of Public Health, Erasmus University Medical Center Rotterdam, The Netherlands.
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MeSH Terms
Age Factors
Birth Rate
Cohort Studies
Infertility, Female / etiology,  physiopathology*
Models, Biological
Reproducibility of Results
Sperm Motility / physiology*

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