Document Detail

Validation of the folate food frequency questionnaire with serum and erythrocyte folate and plasma homocysteine.
MedLine Citation:
PMID:  19184765     Owner:  NLM     Status:  MEDLINE    
The aim of the present study was to develop and validate a folate food frequency questionnaire (FFQ)1 designed to measure dietary folate equivalents. The self-administered FFQ containing 39 items and a reference period of 1 month (i.e. the previous month), was validated against three biomarkers: serum and erythrocyte (RBC) folate, and plasma homocysteine (Hcy). Subjects were women (n=99) between the ages of 21 and 87 years. The Pearson correlation coefficients for folate intake and biomarkers were 0.36, 0.34 and -0.25 for serum and RBC folate, and plasma Hcy, respectively. A principal component factor analysis was performed on the three biomarkers to calculate the folate status factor. The Pearson correlation for the folate status factor and folate intake was 0.39. The FFQ described in this study is a valid tool for measuring folate intake expressed as dietary folate equivalents in adult women and is suitable for future investigations about the relationship between folate and disease, or as an educational tool.
Irena Coli? Bari?; Zvonimir Satali?; Irena Keser; Ivana Ceci?; Martina Suci?
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies     Date:  2009-01-30
Journal Detail:
Title:  International journal of food sciences and nutrition     Volume:  60 Suppl 5     ISSN:  1465-3478     ISO Abbreviation:  Int J Food Sci Nutr     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-16     Completed Date:  2010-07-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9432922     Medline TA:  Int J Food Sci Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  10-8     Citation Subset:  IM    
Laboratory for Food Chemistry and Nutrition, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia.
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MeSH Terms
Aged, 80 and over
Biological Markers / blood
Body Mass Index
Diet Surveys*
Erythrocytes / chemistry*
Folic Acid / administration & dosage,  blood*
Folic Acid Deficiency* / blood,  diagnosis,  epidemiology
Homocysteine / blood*
Middle Aged
Nutritional Status
Principal Component Analysis
Young Adult
Reg. No./Substance:
0/Biological Markers; 454-28-4/Homocysteine; 59-30-3/Folic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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