Document Detail


Validation data for HPLC/FLD determinations of ochratoxin A in red paprika and black pepper adopting a one-step clean-up procedure.
MedLine Citation:
PMID:  20013447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Validation data for the determination of ochratoxin A (OTA) in two spice matrices, red paprika and black pepper, were obtained for samples prepared with a simplified single-step clean-up column. Extracts of finely ground samples of red paprika and black pepper were prepared and applied to a Mycosep 229 Ochra clean-up column. The purified extract was then subjected to HPLC/FLD analysis. The relative standard deviation for repeatability (RSDr) of the method was 11.8% for red paprika and 9.9% for black pepper. The limit of detection (LOD) value (three times the noise) was estimated as corresponding to the response of an extract derived from a blank matrix (previously washed) and spiked at 1.0 microg kg(-1). The limit of quantitation (LOQ) (three times LOD) was 3.0 microg kg(-1). The performance of the one-step column clean-up procedure appears to be a suitable alternative to commonly used clean-up techniques and allows the precise determination of OTA in two complex matrices.
Authors:
M Bononi; F Gallone; F Tateo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  27     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  249-54     Citation Subset:  IM    
Affiliation:
Laboratori di Ricerche Analitiche e Tecnologiche su Alimenti e Ambiente, Di. Pro.Ve., Faculty of Agriculture, University of Milan, Milan 20133, Italy.
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MeSH Terms
Descriptor/Qualifier:
Black Pepper / chemistry*
Capsicum / chemistry*
Chromatography, High Pressure Liquid / standards*
Limit of Detection
Ochratoxins / analysis*
Reproducibility of Results
Spectrometry, Fluorescence / methods*
Spectrometry, Mass, Electrospray Ionization
Tandem Mass Spectrometry
Chemical
Reg. No./Substance:
0/Ochratoxins; 303-47-9/ochratoxin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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