Document Detail

Validation of US-guided percutaneous venous access and manual compression for studies in swine.
MedLine Citation:
PMID:  12682205     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To validate, in swine, the feasibility, efficacy, and safety of ultrasound (US)-guided vascular access, with manual compression for hemostasis, as an alternative to surgical cutdown. MATERIALS AND METHODS: US-guided femoral vein access was attempted 22 times in eight pigs. Bilateral access was performed in the initial procedure (eight pigs, 16 veins), and unilateral access was performed during follow-up procedures (six pigs, six veins). Two sheath sizes were used: 9 F (in eight veins) and 8 F (in 14 veins). At the completion of each procedure, the vascular sheaths were removed and hemostasis was attempted by manual compression. All animals were followed clinically for at least 24 hours after each access procedure. Bilateral US images of the femoral region were obtained in six pigs (12 puncture sites) 2 weeks after the initial procedure. RESULTS: US-guided femoral vein access was successful in all 22 attempts, including 16 first-time insertions and six subsequent insertions. Hemostasis was achieved with 5 minutes of manual compression in all 22 procedures. No groin complications were identified on clinical follow-up or at necropsy. US imaging of the 12 femoral access points in the six pigs that underwent more than one procedure demonstrated normal femoral veins that compressed appropriately with no evidence of thrombosis or hematoma. CONCLUSION: US-guided femoral vein access, with manual compression used for hemostasis, is a safe and effective method for venous interventions in swine. Moreover, this percutaneous technique allows the same vessel to be reused.
Michael J Wallace; Kamran Ahrar; Kenneth C Wright
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Validation Studies    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  14     ISSN:  1051-0443     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-08     Completed Date:  2003-09-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  481-3     Citation Subset:  IM    
John S. Dunn Center for Radiological Sciences, Section of Vascular and Interventional Radiology, Department of Diagnostic Radiology, the University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030-4009, USA.
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MeSH Terms
Animals, Domestic
Femoral Vein / physiology,  surgery*,  ultrasonography*
Follow-Up Studies
Hemostasis / physiology
Immobilization / physiology
Models, Animal
Models, Cardiovascular
Portacaval Shunt, Surgical
Postoperative Complications / etiology,  physiopathology,  ultrasonography
Ultrasonography, Interventional*
Grant Support

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