| Validation study on the accuracy of echocardiographic measurements of right ventricular systolic function in pulmonary hypertension. | |
| | |
MedLine Citation:
|
PMID: 22230250 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The accuracy of echocardiographic parameters of right ventricular (RV) function has not been sufficiently validated in patients with pulmonary hypertension (PH). The aim of this study was to evaluate whether echocardiographic measurements reliably reflect RV systolic function in PH using cardiac magnetic resonance imaging (CMRI)-derived RV ejection fraction (RVEF) as a gold standard. METHODS: A total of 37 consecutive patients with PH, 20 with pulmonary arterial hypertension, 12 with chronic thromboembolic PH, and five others, were prospectively studied. All patients underwent echocardiography, CMRI, and right-heart catheterization within a 1-week interval. Associations between five echocardiography-derived parameters of RV systolic function and CMRI-derived RVEF were evaluated. RESULTS: All five echocardiography-derived parameters were significantly correlated with CMRI-derived RVEF (percentage RV fractional shortening: r = 0.48, P = .0011; percentage RV area change: r = 0.40, P = .0083; tricuspid annular plane systolic excursion [TAPSE]: r = 0.86, P < .0001; RV myocardial performance index: r = -0.59, P < .0001; and systolic lateral tricuspid annular motion velocity: r = 0.63, P < .0001). Compared with the other indices, TAPSE exhibited the highest correlation coefficient. Of the five echocardiographic measurements, only TAPSE significantly predicted CMRI-derived RVEF in multiple regression analysis (P < .0001). Intraobserver and interobserver reproducibility was favorable for all five indices and was particularly high for TAPSE and systolic lateral tricuspid annular motion velocity. CONCLUSIONS: Echocardiographic measurements are promising noninvasive indices of RV systolic function in patients with PH. In particular, TAPSE is superior to other indices in accuracy. |
| | |
Authors:
|
Takahiro Sato; Ichizo Tsujino; Hiroshi Ohira; Noriko Oyama-Manabe; Asuka Yamada; Yoichi M Ito; Chisa Goto; Taku Watanabe; Shinji Sakaue; Masaharu Nishimura |
Publication Detail:
|
Type: Journal Article; Validation Studies Date: 2012-01-09 |
Journal Detail:
|
Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 25 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-02-22 Completed Date: 2012-06-28 Revised Date: 2012-08-22 |
Medline Journal Info:
|
Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
|
Languages: eng Pagination: 280-6 Citation Subset: IM |
Copyright Information:
|
Copyright © 2012 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
First Department of Medicine, Hokkaido University Hospital, Sapporo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Echocardiography
/
instrumentation* Female Heart Ventricles / drug effects, ultrasonography* Humans Hypertension, Pulmonary / pathology, ultrasonography* Magnetic Resonance Imaging, Cine / instrumentation Male Middle Aged Regression Analysis Reproducibility of Results Statistics as Topic Stroke Volume / physiology Systole Ventricular Function, Right / physiology* |
| Comments/Corrections | |
Comment In:
|
J Am Soc Echocardiogr. 2012 Jul;25(7):804
[PMID:
22607886
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoie...
Next Document: The characterization of fibrocyte-like cells: A novel fibroblastic cell of the placenta.