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Validation of QMR Body Composition Analysis for Infants using Piglet Model.
MedLine Citation:
PMID:  21150693     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A study was conducted to validate the use of a quantitative magnetic resonance (QMR) device for measuring the body composition of infants and neonates weighing less than 12 kg using the pig as a model. A total of 25 piglets weighing between 2 and 12 kg were studied. Body composition was assessed by QMR, dual-energy X-ray absorptiometry (DXA), and whole-body chemical analysis (CA) of carcass for lipid and water content. The precision, mean standard deviation of repeated measurements, of QMR to estimate fat mass (FM), lean mass (LM) and total body water (TBW) for five consecutive scans with reposition was 12.5, 32.0 and 36.0 grams respectively. QMR measures of FM, LM and TBW were highly and significantly correlated with CA of carcass. In terms of accuracy, mean difference between QMR and CA (percent of mean value for CA), QMR overestimated FM by 40 g (4.7 %), overestimated LM by 114.9 g (2.1 %), and underestimated TBW by 134.6 g (3.1 %). This study concludes that QMR provides precise and accurate measures of FM, LM and TBW in piglet weighing up to 12 kg. These results suggest that QMR can provide valuable body composition data in longitudinal studies in infants. ABBREVIATIONS::
Authors:
Alva D Mitchell
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-9
Journal Detail:
Title:  Pediatric research     Volume:  -     ISSN:  1530-0447     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Animal Bioscience and Biotechnology Laboratory [ADM], USDA-ARS, Beltsville, MD, USA 20715.
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