Document Detail


Validation of the Forced Oscillation Technique in the diagnostic of respiratory changes in patients with silicosis.
MedLine Citation:
PMID:  21096531     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Silicosis is a typical occupational respiratory disease characterized by irreversible alterations throughout the alveolar and interstitial structure. The objectives of this study were (1) investigate the potential of the Forced Oscillation Technique (FOT) in the analysis of the patients with silicosis, and (2) evaluate the ability of FOT to identify early alterations in the respiratory mechanics of these patients. Sixty-one volunteers were analyzed: 20 healthy subjects and 41 with silicosis; these, were divided into 4 groups according to spirometric results: normal spirometric exam (n = 11); mild obstruction (n = 20); moderate and severe obstruction (n = 10.). A significant (p〈0.0001) increase in total resistance (R0) and mean resistance (Rm) were observed, as well as a decrease in the dynamic compliance (p〈0.0003) and mean reactance (p〈0.000004). R0 and Rm obtained adequate accuracy for clinical use (>80%). FOT parameters adequately described the pathophysiological changes associated with silicosis and presented adequate accuracy for clinical use, indicating that this technique can be helpful in the evaluation respiratory mechanics in this disease.
Authors:
P M Sa; A D Faria; A S Ferreira; A J Lopes; J M Jansen; P L Melo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference     Volume:  1     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  398-401     Citation Subset:  IM    
Affiliation:
Biomedical Instrumentation Laboratory, Institute of Biology, Faculty of Engineering, State University of Rio de Janeiro, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Two dimensional spatial coherence of the natural vibrations of the biceps brachii muscle generated d...
Next Document:  Study to prevent the density of microcapsules from diffusing in blood vessel by local acoustic radia...