Document Detail

Validation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for the Australian and New Zealand population.
MedLine Citation:
PMID:  21810146     Owner:  NLM     Status:  Publisher    
SUMMARY AT A GLANCE: This study validates the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR), a disease-specific patient reported outcome measure, in an Australian and New Zealand population with pulmonary arterial hypertension. Results indicate the CAMPHOR is valid and reliable in this population. ABSTRACT: Background and objective:  Individuals with pulmonary arterial hypertension (PAH) experience severely impaired quality of life. A disease-specific patient reported outcome measure for PAH (the Cambridge Pulmonary Hypertension Outcome Review - CAMPHOR) has recently been developed and validated in the UK, USA and Canada. It has demonstrated reliability and validity in PAH populations in these countries. The aim of this study was to assess the reliability and validity of the CAMPHOR in an Australian and New Zealand (NZ) PAH population. Methods:  Semi-structured interviews were conducted with a cohort of 15 PAH patients (aged 68.9±10.0 yrs; 11 females) to determine the relevance of the CAMPHOR and ensure the terminology and language used was understandable and appropriate for our PAH population. The test-retest reliability, internal consistency and construct validity of the CAMPHOR were then examined in an Australian and NZ PAH population (n = 61, aged 56.9 ± 14.5 yrs; 48 females). Results:  Data from the patient interviews confirmed that the CAMPHOR is appropriate for use in our PAH population. The three CAMPHOR scales (symptoms, activity limitations and quality of life) had excellent test-retest reliability (correlation coefficients [r(s) ]= 0.86 to 0.94, p < 0.01) and internal consistency (Cronbach's alpha coefficients = 0.89 to 0.92). The CAMPHOR also demonstrated the ability to distinguish between individuals with PAH who differed according to World Health Organisation functional class. Conclusions:  We have shown the CAMPHOR to be valid and reliable in an Australian and NZ PAH population and recommend its use in clinical practice.
Louise Ganderton; Sue Jenkins; Stephen P McKenna; Kevin Gain; Robin Fowler; James Twiss; Eli Gabbay
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-2
Journal Detail:
Title:  Respirology (Carlton, Vic.)     Volume:  -     ISSN:  1440-1843     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9616368     Medline TA:  Respirology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors. Respirology © 2011 Asian Pacific Society of Respirology.
School of Physiotherapy and Curtin Health Innovation Research Institute, Curtin University, Perth, Australia Royal Perth Hospital, Perth, Australia Lung Institute of Western Australia, Centre for Asthma, Allergy and Respiratory Research, University of Western Australia Galen Research Ltd, Manchester, United Kingdom Sir Charles Gairdner Hospital, Perth, Australia School of Medicine and Pharmacology, University of Western Australia, Perth, Australia School of Medicine, University of Notre Dame, Fremantle, Australia.
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