Document Detail


Valepotriates and valerenic acids in commercial preparations of valerian available in Australia.
MedLine Citation:
PMID:  11817170     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty-one commercial valerian preparations available in Australia, including teas, tablets, capsules and liquids, were analysed by HPLC for valepotriates, valerenic acid and valerenic acid derivatives. The concentration of valerenic acid and its derivatives ranged from < 0.01 to 6.32 mg/g of product. Powder capsules, on average, contained the highest concentration of valerenic acids (2.46 mg/g) and liquids the lowest concentration (0.47 mg/ml). The mean concentration of valerenic acid in the five products standardized against valerenic acid (3.56 mg/g) was significantly higher than in the 26 non-standardized products (0.89 mg/g). There was a significant relationship between valerenic acids content and added valerian root for the standardized products but not for the non-standardised products. Valepotriates were found at low levels (< 1.0 mg/g) in some teas but were not detected in any of the finished products.
Authors:
D Shohet; R B Wills; D L Stuart
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Die Pharmazie     Volume:  56     ISSN:  0031-7144     ISO Abbreviation:  Pharmazie     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-05     Completed Date:  2002-01-30     Revised Date:  2007-01-29    
Medline Journal Info:
Nlm Unique ID:  9800766     Medline TA:  Pharmazie     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  860-3     Citation Subset:  IM    
Affiliation:
Centre for the Advancement of Food Technology and Nutrition, University of Newcastle, Ourimbah, Australia. ftds@cc.newcastle.edu.au
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MeSH Terms
Descriptor/Qualifier:
Australia
Capsules
Chromatography, High Pressure Liquid
Indenes / analysis*
Iridoids*
Pharmaceutical Solutions
Pyrans / analysis*
Quality Control
Reference Standards
Sesquiterpenes*
Spectrophotometry, Ultraviolet
Tablets
Valerian / chemistry*
Chemical
Reg. No./Substance:
0/Capsules; 0/Indenes; 0/Iridoids; 0/Pharmaceutical Solutions; 0/Pyrans; 0/Sesquiterpenes; 0/Tablets; 0/valtrates (combination); 3569-10-6/valerenic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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