| Vagus nerve stimulation might have a unique effect in reflex eating seizures. | |
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MedLine Citation:
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PMID: 19780799 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the effects of vagus nerve stimulation (VNS) on eating seizures, which theoretically would be triggered by neural activity and signaling from organs innervated by the vagus nerve. Three adult patients with daily nonreflex and reflex eating seizures were studied; one patient also had hot-water seizures. One patient had bilateral polymicrogyria and two had normal magnetic resonance imaging (MRI) findings. All patients were submitted to VNS implantation and had at least 2 years of postimplantation follow-up. Final stimulation parameters were 2.0-2.5 mA, 500 micros, and 30 Hz. Eating seizures decreased 70-95% and nonreflex seizures decreased 0-40% after VNS. There was no improvement in hot-water seizures. VNS seems to be an especially useful treatment modality in patients with reflex eating seizures not amenable to resective surgery. |
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Authors:
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Arthur Cukiert; Pedro Paulo Mariani; Jose Augusto Burattini; Cristine Mella Cukiert; Cassio Forster; Carla Baise; Meire Argentoni-Baldochi; Valeria Mello |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-09-22 |
Journal Detail:
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Title: Epilepsia Volume: 51 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-24 Completed Date: 2010-04-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 301-3 Citation Subset: IM |
Affiliation:
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Epilepsy Surgery Program, Hospital Brigadeiro, S?o Paulo, Brazil. acukiert@uol.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticonvulsants / therapeutic use Combined Modality Therapy Electrodes, Implanted Electroencephalography / statistics & numerical data Epilepsy, Complex Partial / diagnosis, surgery, therapy Epilepsy, Reflex / diagnosis, surgery, therapy* Epilepsy, Temporal Lobe / diagnosis, surgery, therapy Female Follow-Up Studies Functional Laterality / physiology Humans Longitudinal Studies Magnetic Resonance Imaging Male Prognosis Treatment Outcome Vagus Nerve Stimulation / methods* |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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