Document Detail

Vagus nerve stimulation might have a unique effect in reflex eating seizures.
MedLine Citation:
PMID:  19780799     Owner:  NLM     Status:  MEDLINE    
We studied the effects of vagus nerve stimulation (VNS) on eating seizures, which theoretically would be triggered by neural activity and signaling from organs innervated by the vagus nerve. Three adult patients with daily nonreflex and reflex eating seizures were studied; one patient also had hot-water seizures. One patient had bilateral polymicrogyria and two had normal magnetic resonance imaging (MRI) findings. All patients were submitted to VNS implantation and had at least 2 years of postimplantation follow-up. Final stimulation parameters were 2.0-2.5 mA, 500 micros, and 30 Hz. Eating seizures decreased 70-95% and nonreflex seizures decreased 0-40% after VNS. There was no improvement in hot-water seizures. VNS seems to be an especially useful treatment modality in patients with reflex eating seizures not amenable to resective surgery.
Arthur Cukiert; Pedro Paulo Mariani; Jose Augusto Burattini; Cristine Mella Cukiert; Cassio Forster; Carla Baise; Meire Argentoni-Baldochi; Valeria Mello
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-22
Journal Detail:
Title:  Epilepsia     Volume:  51     ISSN:  1528-1167     ISO Abbreviation:  Epilepsia     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-24     Completed Date:  2010-04-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  301-3     Citation Subset:  IM    
Epilepsy Surgery Program, Hospital Brigadeiro, S?o Paulo, Brazil.
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MeSH Terms
Anticonvulsants / therapeutic use
Combined Modality Therapy
Electrodes, Implanted
Electroencephalography / statistics & numerical data
Epilepsy, Complex Partial / diagnosis,  surgery,  therapy
Epilepsy, Reflex / diagnosis,  surgery,  therapy*
Epilepsy, Temporal Lobe / diagnosis,  surgery,  therapy
Follow-Up Studies
Functional Laterality / physiology
Longitudinal Studies
Magnetic Resonance Imaging
Treatment Outcome
Vagus Nerve Stimulation / methods*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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