| Vagus nerve stimulation for drop attacks in a pediatric population. | |
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MedLine Citation:
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PMID: 20800554 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A retrospective analysis of 43 patients with drop attack seizures who were treated with vagus nerve stimulation (VNS) was undertaken to determine the efficacy of VNS and to determine pre-implantation characteristics associated with VNS success. It was found that on last follow-up, 46% of patients had at least a 75% reduction in drops per day. Forty-six percent of patients had less than a 50% reduction in drops per day and were considered nonresponders. Univariate analysis failed to uncover significant associations between pre-implantation characteristics and VNS success. It was found that atonic head nods were more amenable to VNS treatment as compared with atonic or tonic drop attacks. In addition, patients with focal or lateralized epileptiform abnormalities responded better to VNS compared with those with more diffuse or poorly localized findings on ictal and/or interictal recordings. Our data suggest that VNS offers significant palliative benefit to many children with medically intractable drop attack seizures. |
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Authors:
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Muhammad M Abd-El-Barr; Jacob R Joseph; Rebecca Schultz; Joseph L Edmonds; Angus A Wilfong; Daniel Yoshor |
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Publication Detail:
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Type: Journal Article Date: 2010-08-25 |
Journal Detail:
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Title: Epilepsy & behavior : E&B Volume: 19 ISSN: 1525-5069 ISO Abbreviation: Epilepsy Behav Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100892858 Medline TA: Epilepsy Behav Country: United States |
Other Details:
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Languages: eng Pagination: 394-9 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Section of Pediatric Neurology, Baylor College of Medicine, Houston, TX, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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