| Vagus nerve stimulation as a strategy to prevent and manage metabolic syndrome. | |
| | |
MedLine Citation:
|
PMID: 21144670 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
An increase in pro-inflammatory cytokines, decrease in endothelial nitric oxide (eNO) and adiponectin levels and an alteration in hypothalamic peptides and gastrointestinal hormones such as incretins and cholecystokinin that regulate satiety, hunger, and food intake occur in metabolic syndrome. Thus, metabolic syndrome is a low-grade systemic inflammatory condition and could be due to inappropriate cross-talk between the peripheral tissues and the hypothalamic centers implying that methods designed to restore these two abnormalities to normal could be of significant benefit in metabolic syndrome. Vagus nerve stimulation has been shown to suppress inflammation and acetylcholine, the principal vagal neurotransmitter, modulates the actions of several hypothalamic peptides and incretins and cholecystokinin. Based on these evidences, it is proposed that vagus nerve stimulation could be of significant benefit in the management of the metabolic syndrome. |
| | |
Authors:
|
Undurti N Das |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2010-12-6 |
Journal Detail:
|
Title: Medical hypotheses Volume: - ISSN: 1532-2777 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
|
School of Biotechnology, Jawaharlal Nehru Technological University, Kakinada 533 003, India; UND Life Sciences, 13800 Fairhill Road, #321, Shaker Heights, OH 44120, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Electricity and fishing - a dangerous mix.
Next Document: Routinely using prophylactic antibiotic may not effectively prevent intervertebral disc infection: A...