| Vaginal microbicides can interfere with nucleic acid amplification tests used for the diagnosis of Chlamydia trachomatis and Neisseria gonorrhoeae infection. | |
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MedLine Citation:
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PMID: 16860515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We confirmed findings from previous studies that cellulose sulfate gel can interfere with nucleic acid amplification tests used for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae. We therefore recommend that the effects of microbicide gels on diagnostic assays of sexually transmitted infections be established before starting up clinical studies. |
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Authors:
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Tania Crucitti; Vicky Jespers; Lut Van Damme; Eddy Van Dyck; Anne Buvé |
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Publication Detail:
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Type: Clinical Trial, Phase III; Journal Article; Research Support, Non-U.S. Gov't Date: 2006-07-21 |
Journal Detail:
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Title: Diagnostic microbiology and infectious disease Volume: 57 ISSN: 0732-8893 ISO Abbreviation: Diagn. Microbiol. Infect. Dis. Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2006-12-20 Completed Date: 2007-07-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8305899 Medline TA: Diagn Microbiol Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 97-9 Citation Subset: IM |
Affiliation:
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HIV/STD Research and Intervention Unit, Institute of Tropical Medicine,155 Nationalestraat, 2000 Antwerp, Belgium. tcrucitti@itg.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cellulose
/
administration & dosage,
analogs & derivatives*,
pharmacology Chlamydia Infections / diagnosis*, microbiology, prevention & control Chlamydia trachomatis / genetics, isolation & purification Female Gels Gonorrhea / diagnosis*, microbiology, prevention & control Humans Neisseria gonorrhoeae / genetics, isolation & purification Nucleic Acid Amplification Techniques* / standards Specimen Handling / methods Vagina / chemistry*, microbiology |
| Chemical | |
Reg. No./Substance:
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0/Gels; 9004-34-6/Cellulose; 9032-43-3/cellulose sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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