Document Detail

Vaginal inflammatory status in pregnant women with normal and pathogenic microbiota in lower genital tract.
MedLine Citation:
PMID:  21766038     Owner:  NLM     Status:  In-Data-Review    
Objective. To assess the vaginal inflammatory status (VIS) in pregnant women, whether symptomatic or asymptomatic, by leukocyte quantification in relation to the microbiota during each pregnancy trimester (T). Materials and Methods. A thousand two hundred and forty eight vaginal exudates from pregnant women were prospectively examined. All the patients underwent a clinical and colposcopic examination and a microbiological study of vaginal exudates. Leukocyte quantification was determined by May-Grunwald Giemsa staining as LNR per field (400X). Results. Statistically significant differences (SSD) in LNR were observed in the VIS of asymptomatic patients (AP) compared with that of symptomatic ones (SP) with normal microbiota: 10-15 for the 1st T, <10, 20 to 25 and >25 for the 2nd T and >25 for the 3rd; with candidiasis: <10 for the 1st T, <10, 15 to 20 and >25 for the 2nd T and <10 and >25 for the 3rd T. In women with trichomoniasis, SSD in the LNR were observed between SP with LNR ≥ 10 and AP with NLR < 10 in the three trimesters altogether. In women with BV, no SSD were observed in the LNR of any AP with respect to SP for the three T. Conclusion. The VIS is influenced by vaginal microbiota and depends on the state of pregnancy and also, on gestational age. The pronounced leukocyte increase in asymptomatic patients in the absence of lower genital tract infection during the third trimester of pregnancy should be highlighted.
Sebastián Galiñanes; Enrique Coppolillo; Maximiliano Cifarelli; Martha Cora Eliseht; Ercilia Pellisa; Mirta Losada; Sebastián Gruccio; Hilda Ruda Vega; Carlos Vay; Angela Famiglietti; Beatriz Perazzi
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Publication Detail:
Type:  Journal Article     Date:  2011-04-26
Journal Detail:
Title:  ISRN obstetrics and gynecology     Volume:  2011     ISSN:  2090-4444     ISO Abbreviation:  ISRN Obstet Gynecol     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101558763     Medline TA:  ISRN Obstet Gynecol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  835926     Citation Subset:  -    
Clinical Bacteriology Laboratory, Department of Clinical Biochemistry, Hospital de Clínicas, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Córdoba 2351, 1120, City of Buenos Aires, Argentina.
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