Document Detail


Vagifem is superior to vaginal Premarin in induction of endometrial thickness in the frozen-thawed cycle patients with refractory endometria: A randomized clinical trial.
MedLine Citation:
PMID:  25071850     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Embryo transfer to a developed endometrium is an important prognostic factor in frozen-thawed embryo transfer cycle outcome. Vaginal estrogen, such as Vagifem vaginal tablets and Premarin vaginal cream, is a regimen used for the patients with refractive endometria.
OBJECTIVE: Our objective was to compare the effects of Vagifem and Premarin on the endometrial thickness of the patients with refractive endometria.
MATERIALS AND METHODS: In this randomized clinical trial, 30 patients with refractive endometria in frozen-thawed embryo transfer cycles received Vagifem vaginal tablets and 30 women received Premarin vaginal cream. Endometrial thickness was measured on the 14th day of drug administration.
RESULTS: Comparing the endometrial thicknesses of the two groups showed that the endometria of the Vagifem group was significantly thicker than that of the Premarin group (5.93±0.38 vs. 6.74±0.32; p<0.001).
CONCLUSION: Vagifem is superior to Premarin in induction of endometrial thickness in frozen-thawed embryo transfer cycles in the patients with refractive endometria.
Authors:
Jaleh Zolghadri; Hossein Haghbin; Nasrin Dadras; Shabnam Behdin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Iranian journal of reproductive medicine     Volume:  12     ISSN:  1680-6433     ISO Abbreviation:  Iran J Reprod Med     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-07-29     Completed Date:  2014-07-29     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101463749     Medline TA:  Iran J Reprod Med     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  415-20     Citation Subset:  -    
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